A panel of experts in dementia discusses the latest progress in the treatment of Alzheimer disease, and the various therapies that have progressed through the pipeline.
EP. 1: Current Understanding of Alzheimer’s Disease Pathology
Four Alzheimer’s disease expert discuss our current understanding of Alzheimer’s disease pathology and the presence of amyloid and tau pathologies in patients.
EP. 2: Biomarkers and Challenges to the Use of Biomarkers in Alzheimer’s Disease
Drs Atri and Cohen discuss biomarkers for Alzheimer’s disease and the challenges in their use in routine practice.
EP. 3: Genetic and Structural Heterogeneity in Alzheimer’s Disease
Drs McDade and Sabbagh discuss heterogeneity in Alzheimer’s disease and structural polymorphism and genetic mosaicism seen in patients.
EP. 4: Ongoing Research and Use of Biomarkers and Imaging in Alzheimer’s Disease
Dr Atri shares his excitement about ongoing research and the use of biomarkers and imaging for management Alzheimer’s disease.
EP. 5: Diagnostic Pathway for Alzheimer’s Disease
Dr. Atri discusses his approach to diagnosis and Dr. McDade updates on the use of tau-PET for diagnosis of Alzheimer’s disease.
EP. 6: Importance of Primary Care Physicians in Diagnosis of Alzheimer’s Disease
Dr Cohen emphasizes the importance of engagement of primary care physicians in identification of Alzheimer’s disease symptoms and pathology.
EP. 7: Use of ATN Classification for Alzheimer’s Disease in Clinical Practices
Drs McDade and Cohen discuss ATN (amyloid, tau, neurodegeneration) classification and its use in clinical practice to manage Alzheimer’s disease.
EP. 8: Factors Contributing to Clinical Trial Failures in Alzheimer’s Disease
Dr. Cohen shares factors that may have contributed to the high failure rate of Alzheimer’s disease clinical trials thus far.
EP. 9: Considerations for Management of Alzheimer’s Disease
Dr Atri discusses considerations and suggestions for caring for patients with Alzheimer’s disease.
EP. 10: Current Treatment Options for Alzheimer’s Disease
Dr Cohen shares current treatment options for Alzheimer’s disease and how she manages these patients in her practice.
EP. 11: Management of Neuropsychiatric symptoms of Alzheimer’s Disease
Dr Atri emphasizes importance of managing neuropsychiatric symptoms in patients with Alzheimer’s disease and drugs under development.
EP. 12: Treatment Pipeline for Alzheimer’s Disease
Drs McDade, Atri, Cohen, and Sabbagh discuss candidates drugs and various mechanisms of actions that are currently under evaluation for Alzheimer’s disease.
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