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Articles

Takeda reveals promising phase 3 results for oveporexton, a potential breakthrough treatment for narcolepsy type 1, targeting excessive daytime sleepiness.

Orexin-Targeting Agent TAK-861 Meets All End Points in Phase 3 FirstLight and RadiantLight Studies

Recently reported phase 2b results revealed that PrimeC consistently altered ALS-related miRNA expression, reinforcing its potential as a multi-targeted therapy and aligning with previously reported clinical benefits. 

Late-Breaking Phase 2b PARADIGM Data Support Continued Development of PrimeC in ALS

Videos

The movement disorder specialist and patient living with Parkinson disease highlighted the need for a more human-centered approach in managing chronic and progressive movement disorders. [WATCH TIME: 6 minutes]

Centering Empathy in Parkinson Care by Listening Beyond the Diagnosis: María L. De León, MD

Here's some of what is coming soon to NeurologyLive® this week. 

This Week on NeurologyLive® — July 14, 2025

The associate professor of medicine at the Icahn School of Medicine at Mount Sinai outlined emerging interventions aimed at enhancing glymphatic clearance to potentially lower Alzheimer disease risk. [WATCH TIME: 4 minutes]

Exploring Tools to Target the Glymphatic System and Alzheimer Disease Risk: Andrew Varga, MD

Movement disorder specialist and patient living with Parkinson disease.

Associate professor, Ferkauf Graduate School of Psychology, Yeshiva University, and associate professor, department of neurology, Albert Einstein College of Medicine.

The professor of neurology at Albert Einstein College of Medicine talked about new findings presented at AHS, which suggested that both men and women with migraine can face significantly increased risks of ischemic stroke. [WATCH TIME: 5 minutes]

Using Veterans Health Data to Gain Insights on Sex Differences in Migraine and Stroke Risk: Elizabeth Seng, PhD

The associate professor of neurology at Mayo Clinic College of Medicine discussed findings presented at AHS 2025 from a post hoc analysis of the phase 3b DELIVER study testing eptinezumab in patients with migraine. [WATCH TIME: 5 minutes]

Assessing Eptinezumab’s Impact in Reducing Migraine Burden Through Longer Interictal Periods: Amaal Starling, MD, FAHS, FAAN

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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Management of Insomnia in Female Patients  

An expert discusses the frontline management of insomnia in female patients.

Charlene Gamadelo, MD, provides an overview of insomnia and discusses the prevalence by race and gender, the variations in presentation of symptoms in patients, and the pathways involved in sleep wakefulness cycles.

Overview of Insomnia

A neurology expert describes why women experience insomnia at higher rates than men and how co-occurrence of insomnia with other medical conditions, including psychiatric disorders, can affect occurrence. 

Insomnia in Female Patients

An overview of the impact insomnia can have on female patient’s quality of life and how they communicate sleep disturbance concerns with health care professionals.

Quality of Life and Patient Communication Regarding Insomnia

An overview of the different roles of health care professionals in the management of female patients suffering from insomnia.

Managing Female Patients With Insomnia

Charlene Gamadelo, MD, provides an overview of commonly utilized insomnia treatment modalities in the treatment of female patients with insomnia.

Approach to Treating Female Patients With Insomnia

Charlene Gamadelo, MD, describes the different categories of FDA approved treatments for insomnia along with challenges associated with these treatments.

Challenges Associated With Insomnia Treatments

An overview of dual orexin receptor agonists (DORAs) therapy for the treatment of insomnia in female patients.

Insomnia Treatment: DORAs

Charlene Gamaldo, MD, discusses patient criteria for selecting a dual orexin receptor agonist (DORA) for insomnia treatment.

Insomnia Treatment Selection: DORA

Lasso - DMD Peers and Perspectives NSP-21-NRD0157

Clinical

 video series brings together pairs of expert clinicians and physicians to independently provide their insights on the latest and most up-to-date clinical care for specific neurologic diseases and disorders.

Challenges Associated With Insomnia Treatments

EP: 1.Overview of Insomnia

EP: 2.Insomnia in Female Patients

EP: 3.Quality of Life and Patient Communication Regarding Insomnia

EP: 4.Managing Female Patients With Insomnia

EP: 5.Approach to Treating Female Patients With Insomnia

EP: 6.Challenges Associated With Insomnia Treatments

EP: 7.Insomnia Treatment: DORAs

EP: 8.Insomnia Treatment Selection: DORA

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