News|Articles|June 27, 2026

Improving Recognition of Autonomic Dysfunction in Parkinson Disease: Insights With Jonathan Isaacson, MD; and Abhishek Lenka, MD, PhD

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Movement disorder experts Jonathan Isaacson, MD, and Abhishek Lenka, MD, PhD, discuss early identification and accurate diagnosis of autonomic dysfunction in Parkinson disease, highlighting emerging biomarkers and monitoring tools that may enable more personalized care.

Autonomic dysfunction is a common yet frequently underrecognized feature of Parkinson disease (PD), contributing to symptoms that can affect quality of life and may be associated with increased morbidity and mortality. Conditions such as orthostatic hypotension, supine hypertension, and pure autonomic failure often present with nonspecific symptoms, making diagnosis challenging and potentially delaying appropriate treatment.