Our Feb. news & research include two new migraine drugs, the stroke-Parkinson link, and the potential of an anticancer drug to prevent Alzheimer.
We present a selection of interesting neurology articles for the month of February in the following slides. See the slide legends for links to the article summaries.
Interesting Neurology: migraine drugs & stroke risks. February 2016
The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain. Abstract link. **** An Anticancer Drug Suppresses the Primary Nucleation Reaction that Initiates the Production of the Toxic Aβ42 Aggregates Linked with Alzheimer’s Disease. Abstract link.
Screening for Autism Spectrum Disorder in Young Children. US Preventive Services Task Force Recommendation Statement. Abstract link.****Sleep and Behavioral Problems in Children with Autism Spectrum Disorder. Abstract link.
Hippocampal Deep Brain Stimulation in Nonlesional Refractory Mesial Temporal Lobe Epilepsy. Abstract link. **** Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Abstract link.
Migraine Is Related to an Increased Risk of Parkinson’s Disease: a Population-Based, Propensity Score-Matched, Longitudinal Follow-up Study. Abstract link.****Safety and Efficacy of AMG 334 for Prevention of Episodic Migraine: a Randomised, Double-Blind, Placebo-Controlled, Phase 2 Trial. Abstract link.
Avanir Pharmaceuticals Announces FDA Approval of ONZETRA⢠Xsail⢠(AVP-825) for the Acute Treatment of Migraine in Adults. Press release. ****Dr. Reddy’s Laboratories Ltd. Receives FDA Approval for ZEMBRACEâ¢SymTouch⢠(sumatriptan succinate) Injection for the Acute Treatment of Migraines in Adults. Press release.
Risk of Early Relapse Following the Switch from Injectables to Oral Agents for Multiple Sclerosis. Abstract Link. ****Taste Dysfunction in Multiple Sclerosis. Abstract link.
Nestin-Positive/SOX2âNegative Cells Mediate Adult Neurogenesis of Nigral Dopaminergic Neurons in Mice. Abstract link. ****Pharmacodynamics of a Low Subacute Levodopa Dose Helps Distinguish Between Multiple System Atrophy with Predominant Parkinsonism and Parkinson’s Disease. Abstract link.
Polygenic Risk of Ischemic Stroke Is Associated with Cognitive Ability. Abstract link.****Differences in the Role of Black Race and Stroke Risk Factors for First vs Recurrent Stroke. Abstract link.