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Interesting Neuro: migraine drugs & stroke risks

Our Feb. news & research include two new migraine drugs, the stroke-Parkinson link, and the potential of an anticancer drug to prevent Alzheimer.

We present a selection of interesting neurology articles for the month of February in the following slides. See the slide legends for links to the article summaries.

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Interesting Neurology: migraine drugs & stroke risks. February 2016

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The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain. Abstract link. **** An Anticancer Drug Suppresses the Primary Nucleation Reaction that Initiates the Production of the Toxic Aβ42 Aggregates Linked with Alzheimer’s Disease. Abstract link.

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Screening for Autism Spectrum Disorder in Young Children. US Preventive Services Task Force Recommendation Statement. Abstract link.****Sleep and Behavioral Problems in Children with Autism Spectrum Disorder. Abstract link.

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Hippocampal Deep Brain Stimulation in Nonlesional Refractory Mesial Temporal Lobe Epilepsy. Abstract link. **** Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Abstract link.

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Migraine Is Related to an Increased Risk of Parkinson’s Disease: a Population-Based, Propensity Score-Matched, Longitudinal Follow-up Study. Abstract link.****Safety and Efficacy of AMG 334 for Prevention of Episodic Migraine: a Randomised, Double-Blind, Placebo-Controlled, Phase 2 Trial. Abstract link.

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Avanir Pharmaceuticals Announces FDA Approval of ONZETRA™ Xsail™ (AVP-825) for the Acute Treatment of Migraine in Adults. Press release. ****Dr. Reddy’s Laboratories Ltd. Receives FDA Approval for ZEMBRACE™SymTouch™ (sumatriptan succinate) Injection for the Acute Treatment of Migraines in Adults. Press release.

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Risk of Early Relapse Following the Switch from Injectables to Oral Agents for Multiple Sclerosis. Abstract Link. ****Taste Dysfunction in Multiple Sclerosis. Abstract link.

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Nestin-Positive/SOX2−Negative Cells Mediate Adult Neurogenesis of Nigral Dopaminergic Neurons in Mice. Abstract link. ****Pharmacodynamics of a Low Subacute Levodopa Dose Helps Distinguish Between Multiple System Atrophy with Predominant Parkinsonism and Parkinson’s Disease. Abstract link.

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Polygenic Risk of Ischemic Stroke Is Associated with Cognitive Ability. Abstract link.****Differences in the Role of Black Race and Stroke Risk Factors for First vs Recurrent Stroke. Abstract link.

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