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Articles

An IDMC review of unblinded interim data was positive and advised that the trials continue as planned, with time to first relapse up to 72 weeks as the primary end point.



Phase 3 ENSURE Program of Vidofludimus Calcium Continues Following Positive Futility Analysis

With the positive recommendation, it marks a key step toward eplontersen’s availability in Europe as a treatment for ATTR polyneuropathy.

Eplontersen Gains Positive CHMP Approval Recommendation for ATTR Polyneuropathy

The 2024 revisions to the McDonald diagnostic criteria for multiple sclerosis (MS) mark a significant advancement in the early detection and diagnosis of the disease, with new biomarkers and a broadened scope that may lead to earlier intervention and improved patient outcomes.

Revised McDonald Diagnostic Criteria Signals New Era in Multiple Sclerosis Treatment

Constantine Farmakidis, MD, an associate professor of neurology at the University of Kansas Medical Center, provided clinical commentary on a subanalysis of a phase 3 study assessing nipocalimab, an investigational agent, in generalized myasthenia gravis.

Understanding Nipocalimab’s Impact on Myasthenia Gravis Using MG-ADL

Associate Professor of Neurology, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University; staff neurologist, Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic

, has been with the team since October 2019. Follow him on Twitter 

Videos

Beyond the Guidelines: Monitoring and Defining SMA Progression

In this segment, the panel discussed adult-onset 5q spinal muscular atrophy (SMA), highlighting its frequent underdiagnosis and subtle symptoms such as cramps, fasciculations, and sports intolerance.

Adult-Onset SMA: Diagnosis and Best Practices for Clinicians

The discussion highlighted the need for national or local protocols, insurance approvals, and close collaboration with families to optimize patient outcomes.

Optimizing Treatment Access in SMA: Navigating Timing and Outcomes

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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We present a selection of interesting neurology articles for the month of March in the following slides. See the slide legends for links to the article summaries.

Slideshows

March news includes possible brain tumor therapies, a study exploring mechanisms underlying demyelination-induced seizures, and VNS post stroke.

Interesting Neuro: Tumor Tx and Stroke Recovery