NeurologyLive Friday 5 — February 26, 2021

Welcome to NeurologyLive's Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive's widespread coverage in neurology, ranging from newsworthy study findings and FDA action to expert interviews and peer-to-peer panel discussions.

1: Mind Moments: Cognitive Behavioral Therapy for Insomnia

"Mind Moments," a podcast from NeurologyLive, brings you an exclusive interview with Jennifer Martin, PhD, professor of medicine, University of California-Los Angeles, and a board member of the American Academy of Sleep Medicine (AASM), to discuss the AASM's recent clinical practice guideline update.

2: Inconsistencies in End Points, Study Design Identified in Migraine Treatment Trials

Investigators noted that empirical work is needed to determine if change from baseline, fixed time point assessments, and responder definitions, or other approaches optimize power and sensitivity to change.

3: Measuring MS Fatigue in a Real-World Setting: Allitia DiBernardo, MD

The global head of medical affairs-neurology at Janssen Pharmaceutical discussed 2 studies presented at the ACTRIMS Forum 2021 involving fatigue among patients with multiple sclerosis.

4: NeuroVoices: Stephen Rao, PhD, and Jay Alberts, PhD, on High-Intensity Exercise in Preventing Alzheimer Disease

The duo from Cleveland Clinic discussed their recently initiated study which will evaluate the neuroprotective features of home-based intervention in high-risk individuals for Alzheimer disease.

5: Cladribine Demonstrates CD19+ B and CD4+ T Lymphocyte Impact Regardless of Age

The effect of cladribine on CD8+ T lymphocytes varied by age, with steady increases shown in the younger population whereas there were fluctuations observed in the older group.

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