Marco Meglio, Assistant Managing Editor for NeurologyLive, has been with the team since October 2019. Follow him on Twitter @marcomeglio1 or email him at mmeglio@neurologylive.com
Clinician-Based Survey Highlights Challenges in Diagnosing Narcolepsy in Children, Adolescents
October 20th 2022When asked which efficacious diagnostic or treatment options they hope to see in the future, a majority of physicians, especially specialists, expressed a desire to see more useful biomarkers, followed by more effective diagnostic tests overall.
Fewer Poststroke Functional Improvement Seen in EVT-Treated Patients With Lower ASPECTS Scores
October 19th 2022More than 40% of patients with ASPECTS scores between 4 and 5 treated with EVT showed functional outcome improvements, whereas slightly over 20% of those with scores between 0 to 3 demonstrated the same.
Phase 3 LIGHTHOUSE Study of LRRK2 Inhibitor BIIB122 Initiated in Parkinson Disease
October 12th 2022Similar to the recently commenced phase 2b LUMA study, BIIB122, an investigational small molecule inhibitor of LRRK2, will be evaluated in a cohort of 400 individuals with genetically mutated Parkinson disease.
NeuroVoices: Wayne Feng, MD, FAHA, on Changing the Approach to Poststroke Neuromuscular Symptoms
October 12th 2022The division chief of stroke and vascular neurology at Duke Health discussed how clinicians have typically treated poststroke motor symptoms and how technology is expanding these capabilities.
Temporal Trends Show Increased Use of Antiseizure Medications With Lower Teratogenic Risk
October 11th 2022Valproic acid, which had been associated with a variety of major and minor malformations in pregnancy, remained barely unchanged in terms of use, dropping slightly from 12.4% to 10.1% over the 5-year period.
Total N-Acetylaspartate Different Across Antibody-Negative Overlapping Multiple Sclerosis, NMOSD
October 8th 2022Using magnetic resonance spectroscopy, investigators observed significantly different levels of total NAA across MS and NMOSD subtypes, and a negative correlation between total NAA and disability score.
Nerivio Remote Electrical Neuromodulation Could Serve as Alternate Treatment for Chronic Migraine
October 4th 2022No statistical differences were found between REN and the standard of care medications, in any of the effectiveness outcomes of pain single-treatment pain relief and pain freedom, nor in consistency of pain relief and pain freedom.
CNM-Au8 Shows Survival Benefit in HEALEY ALS Trial, But Fails to Meet End Points
October 3rd 2022Despite not meeting its primary and secondary end points, CNM-Au8 will continue to be evaluated in an open-label extension in HEALEY ALS and could potentially be offered in an expanded access protocol program.
Reactions, Ramifications, and Forward Progress of Newly Approved AMX0035 for ALS
October 1st 2022Justin Klee and Josh Cohen, cofounders and cochief operating officers, Amylyx Pharmaceuticals, answered questions related to the new approval of AMX0035 for ALS and how it changes the treatment landscape going forward.