SPOTLIGHT -
Therapies for Children and Adults with Dravet Syndrome
The panelists discuss the possibility of treating Dravet syndrome in older children and adults and the effects if the therapies were effective.
Looking to the Future of Dravet Syndrome Therapies
The panel discusses future gene therapies in development for Dravet syndrome.
Transitioning Into Adulthood With Dravet Syndrome
Elaine Wirrell, MD, reviews the transition of care into adulthood of patients with Dravet syndrome and how this transition can affect the patient, caregiver, and care provider.
Impact of Dravet Syndrome on the Caregiver and Family
The panel discusses the impact on the family, siblings, or caregivers of patients with Dravet syndrome.
Fenfluramine as a Treatment Option for Dravet Syndrome
Elaine Wirrell, MD, provides background on fenfluramine, results from 2 clinical trials, and compares it to other treatment therapies.
Cannabidiol as a Treatment Option for Dravet Syndrome
Elizabeth Thiele, MD, PhD, reviews cannabidiol oral solution as treatment of seizures associated with Dravet syndrome and the safety profile and dosing associated with it.
Second- and Third-Line Treatments for Dravet Syndrome
Experts in the field discuss second- and third-line treatment options for Dravet syndrome such as stiripentol and vagal nerve stimulation and the effects they’ve seen on patients.
Treatment Therapies for Dravet Syndrome
A panel discussion on the North American Consensus statement on treating Dravet syndrome and the approved therapies like clobazam, ketogenic diets, and other first- and second-line therapies.
Managing Patient/Parent Expectations in Dravet
A discussion on having conversations with the parents of patients with Dravet syndrome with regards to adjustments to therapy and managing their expectations.
Treatment Variability for Dravet Syndrome
A panel of experts discuss treatment goals for patients with Dravet syndrome and how to convey the variability of treatment to the parents of these patients.
Importance of Early Diagnosis for Dravet Syndrome
Trevor J. Resnick, MD, and Elaine Wirrell, MD, explain why the early diagnosis of Dravet syndrome is important, which patient profiles should be noted for ordering genetic testing, and what to do with those results.
Dravet Syndrome Overview
Elizabeth Thiele, MD, PhD, and Elaine Wirrell, MD, provide an overview of Dravet syndrome and the seizure triggers in pediatric patients.
QoL of Cenobamate in Treatment-Resistant Epilepsy
Using Midazolam Nasal Spray for Seizure Clusters
Interim Analysis of Diazepam Nasal Spray in Epilepsy
BELIEVE Trial: Developmental and Epileptic Encephalopathies
FAME Study: Partial-Onset Seizures
Focal Seizures: Post-hoc Analysis of Cenobamate
ELEKTRA Study in Dravet and Lennox-Gastaut Syndromes
Safety and Efficacy of CBD in Patients With TSC
Clinical Benefit of Fenfluramine in Dravet Syndrome
Phase 4 ELEVATE Study