Advice for Managing Dravet Syndrome and LGS
Mary Anne Meskis; Tracy Dixon-Salazar, PhD; Kelly Knupp, MD; and Joseph E. Sullivan, MD, provide advice for physicians treating patients with Dravet syndrome or LGS.
Resources for Dravet Syndrome and LGS
Kelly Knupp, MD; Mary Anne Meskis; and Tracy Dixon-Salazar, PhD, share education around patient advocacy and support groups as well as other resources for patients with Dravet syndrome or LGS.
Challenges in Treatment Selection in LGS
Tracy Dixon-Salazar, PhD, leads a discussion on challenges of treating LGS and real-world implications from clinical trial data on newer medications.
Approaching Treatment for LGS
Kelly Knupp, MD, provides insight on optimizing treatment for patients with Lennox-Gastaut Syndrome.
Newer Treatments for LGS
Dr Kelly Knupp examines data on fenfluramine and cannabidiol for the management of Lennox-Gastaut Syndrome.
Treatment Options for LGS
Joseph E. Sullivan, MD, leads a discussion on treatment options for the management of patients with LGS and considers the impact of treatment on quality of life.
Goals of Therapy for LGS
Kelly Knupp, MD, shares her perspective of a provider journey of a new patient with LGS and goal setting to manage the disease.
Patient Journey to LGS Diagnosis
Tracy Dixon-Salazar, PhD, reflects on her daughter’s journey to diagnosis of Lennox-Gastaut Syndrome and the impact of the disease on caregivers.
Differential Diagnosis for LGS and Challenges in Managing Seizures
Tracy Dixon-Salazar, PhD, and Kelly Knupp, MD, emphasize key identifiers for the diagnosis of Lennox-Gastaut Syndrome and challenges in managing seizures in these patients.
Overview of Lennox-Gastaut Syndrome (LGS)
Kelly Knupp, MD, provides an overview of Lennox-Gastaut Syndrome (LGS).
Treatment for Patients with Suboptimal Seizure Control
Joseph E. Sullivan, MD, and Kelly Knupp, MD, share strategies for managing patients who have suboptimal seizure control with medications.
Role of Stiripentol in Managing Dravet Syndrome
Joseph E. Sullivan, MD, and Kelly Knupp, MD, evaluate the use of stiripentol in clinical practice for the management of Dravet syndrome and Mary Anne Meskis discusses the honeymoon effect of drugs.
Using Fenfluramine for Dravet Syndrome Treatment
Expert pediatric neurologists assess the use of fenfluramine and comment on its impact on seizure freedom for patients with Dravet syndrome.
Cannabidiol for Dravet Syndrome
Kelly Knupp, MD, reviews available treatment options indicated for Dravet syndrome and shares her thoughts on the use of cannabidiol for patients.
Treatment for Younger Patients Diagnosed With Dravet Syndrome
Kelly Knupp, MD, leads a discussion on goals of treatment for patients who are earlier in their treatment journey.
Updates in Dravet Syndrome: Entering a New Era
Progress in therapeutics and diagnosis over the past decade has dramatically shifted the treatment landscape for this genetic epilepsy and rapidly advanced patient care.
Impact of Dravet Syndrome on QoL
Dr Kelly Knupp, Dr Joseph E. Sullivan, and Mary Anne Meskis comment on the impact of Dravet syndrome on a patient and their caregiver’s quality of life and address education around SUDEP.
Signs and Symptoms of Dravet Syndrome
Kelly Knupp, MD, reviews the patient presentation of Dravet syndrome and the recognition of common signs and symptoms in patients.
Patient Journey to Dravet Syndrome Diagnosis
Kelly Knupp, MD; Joseph E. Sullivan, MD; and Mary Anne Meskis review diagnosis of Dravet syndrome and the role of genetic testing.
Overview and Prevalence of Dravet Syndrome
Kelly Knupp, MD, provides an overview of Dravet syndrome and shares insight on discerning the diagnosis of disease from febrile seizures.
Dravet Syndrome: Transition of Care Into Adulthood
Joseph Sullivan, MD, and Elaine C. Wirrell, discuss the transition of care into adulthood of patients with Dravet syndrome.
Managing Expectations for Patients With Dravet Syndrome
Key opinion leaders discuss managing patient expectations regarding clinical trials for Dravet syndrome treatment.
Therapies in Development for Dravet Syndrome
A discussion of new developments for the treatment of Dravet syndrome beyond seizure control including gene editing and therapy.
Dravet Syndrome: Fenfluramine and the Impact on Consensus Guidelines
The impact of new drug approvals on the consensus guidelines for the treatment of Dravet syndrome.
Therapies for Children and Adults with Dravet Syndrome
The panelists discuss the possibility of treating Dravet syndrome in older children and adults and the effects if the therapies were effective.
Looking to the Future of Dravet Syndrome Therapies
The panel discusses future gene therapies in development for Dravet syndrome.
Recent Approval of Fenfluramine Oral Solution
Joseph Sullivan, MD, provides an overview of the recent approval of fenfluramine oral solution for the treatment of Dravet syndrome.
Dravet Syndrome: Cannabidiol Oral Solution
Elaine C. Wirrell, MD, provides an overview of cannabidiol oral solution for treatment of seizures associated with Dravet syndrome.
Dravet Syndrome: Management of Treatment
Joseph Sullivan, MD, and Elaine C. Wirrell, MD, discuss the management of seizures for Dravet syndrome with different approved therapies.
Treatment Goals of Dravet Syndrome
Experts discuss the goals of treatment of patients with Dravet syndrome regarding seizure freedom and seizure burden.
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