Authors
Latest:
Implementing New Diagnostic Criteria of Limbic-Predominant Amnestic Neurodegenerative Syndrome in Clinical Practice: Nick Corriveau-Lecavalier, PhD & David T. Jones, MDA duo of experts from Mayo Clinic discussed how recent developments in clinical criteria for diagnosing limbic-predominant amnestic neurodegenerative syndrome allow for more accurate differentiation from Alzheimer disease. [WATCH TIME: 9 minutes]
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Unique Composition of CNM-Au8 to Treat MS and ALS: Michael HotchkinThe chief development officer at Clene Nanomedicine provided insight on why CNM-Au8, an investigational agent in development, has shown positive results across both multiple sclerosis and ALS. [WATCH TIME: 2 minutes]
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Understanding the Utility of Specific Antibody Testing in Peripheral Neuropathies: Benjamin Claytor, MDThe assistant professor of neurology at Cleveland Clinic provided insight on the differences in ganglioside vs paranodal antibodies and their clinical use in various neuropathies. [WATCH TIME: 3 minutes]
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Understanding Mechanisms of MS Chronic Inflammation: Jemima Akinsanya, DO, and Daniel Reich, MD, PhDThe duo from the National Institutes of Health discussed how monitoring and treating paramagnetic rim lesions can improve patient care in multiple sclerosis.
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Patient-Centric Theme of SRNA’s 2022 Rare Neuroimmune Disorders Symposium: Carlos A. Pardo-Villamizar, MDThe professor of neurology at Johns Hopkins Medicine provided an in-depth look at the 2022 RNDS and the unique design it offers patients with rare neuroimmune disorders. [WATCH TIME: 3 minutes]
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Benefits of Telemedicine and Access to Treatments for Multiple Sclerosis: Jai Perumal, MDThe associate professor of clinical neurology at Weill Cornell Medicine discussed the progress made in multiple sclerosis in terms of expanding access to therapies and the challenges that persist for progressive forms of the disease in the field. [WATCH TIME: 10 minutes]
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Successes and Challenges in the New Era of Genetic Medicine: Nicholas E. Johnson, MD, MSciThe division chief of neuromuscular disorders and vice-chair of research at Virginia Commonwealth University spoke to the ongoing success in the development of gene-mediated therapies and the challenges that come along with treating rare neuromuscular disease. [WATCH TIME: 3 minutes]
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COVID-19 Shutdowns and the Disruption to Deep Brain Stimulation TreatmentWhile shutdowns disrupted care for all patients with Parkinson disease, hospitals were forced to postpone elective procedures such as the initial DBS device implantation and implantable pulse generator replacements.
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The Promising Future of Gene Therapy in Treating Neurological Diseases: Michael Kaplitt, MD, PhDThe professor of neurological surgery at Weill Cornell medicine talked about how gene therapy may offer a more direct and efficient pathway to develop treatments for neurological diseases like Parkinson disease. [WATCH TIME: 6 minutes]
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Using Data Collection to Improve Parkinson Disease Treatment Personalization: Amanda Hare, DNPThe doctor of nursing practice specialized in movement disorders discussed specific data the StrivePD app captures and how it can enhance quality of life for patients with Parkinson disease. [WATCH TIME: 3 minutes]
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Balancing New Medications and Reducing Adverse Effects in Epilepsy Treatment: Louis Ferrari, RPh, MBAThe vice president of medical affairs at SK Life Science talked about findings from a new post-hoc analysis which highlighted the importance of strategically reducing concomitant medications to minimize adverse events of epilepsy treatment. [WATCH TIME: 5 minutes]
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Digital Health Tool Offers Innovative Quantitative Fall Assessment Solution for Older AdultsFalls cost the US more than $50 billion annually, but platforms like CatchU, a transformative digital health tool, provide quantitative fall assessment that might significantly enhance the current standard of care for predicting falls.
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Improving Stroke Discharge Outcomes: Marian LaMonte, MD, MSN, FAANThe chief of neurology at Ascension Saint Agnes discussed the interventions her team implemented to improve patient-specific stroke discharge instructions.
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A Practical Approach to Chronic Immunosuppression in Myasthenia GravisA practical approach to initiating and tapering corticosteroids, and the considerations in the selection and monitoring parameters of steroid-sparing agents are crucial to the care of myasthenia gravis.
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Using Neuromuscular Function as a Risk Factor for Falls in Multiple Sclerosis: Laurits Taul Madsen, PhD-CThe PhD student at Aarhus University provided insight on his study presented at 2022 ECTRIMS Congress on an innovative way using neuromuscular measures to discriminate those with MS at high risk for falls. [WATCH TIME: 2 minutes]
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Expanding Knowledge on the Role of Neuropilin-1 in Chronic Pain: Nigel Bunnett, PhD, BScThe professor and chair of the Department of Molecular Pathobiology at NYU College of Dentistry discussed how a recently published preclinical study adds to the understanding of neuropilin-1 in chronic pain. [WATCH TIME: 3 minutes]
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Considerations to Better Diagnose Nonhemorrhagic Cerebral Amyloid Angiopathy: Andreas Charidimou, MD, PhDThe neurologist and assistant professor at Boston University Medical Center provided forward thoughts on improving the diagnosis of milder, asymptomatic cases of cerebral amyloid angiopathy. [WATCH TIME: 4 minutes]
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Reactions to FDA Advisory Panel Decision on AMX0035: Justin Klee; Josh Cohen, BScThe co-CEOs and co-founders of Amylyx Pharmaceuticals discussed their immediate thoughts to the recent FDA AdComm meeting, which voted against evidence of efficacy for AMX0035 in ALS. [WATCH TIME: 3 minutes]
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Managing Disease Progression in MS: Changing Treatments and Clinician AdvicePanelists discuss how in multiple sclerosis (MS) treatment, clinicians must strategically evaluate disease progression, considering within-class or mechanism-of-action switches. Comprehensive monitoring, personalized approaches, and proactive management are crucial for optimizing patient outcomes and minimizing long-term neurological disability.
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Applying the Innovation Biodesign Framework to Promote Equity and Green Activity in Dementia CareLassell et al present a use case demonstrating the process of moving an unmet need to the “solution space” of the Innovation Biodesign Framework for addressing a healthcare challenge in a specific at-risk population: Alzheimer disease and AD-related dementias.
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Exploring the Changing Diagnosis and Treatments of Neuromyelitis Optica Spectrum DisorderNeuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune CNS condition with distinct subtypes—AQP4-IgG positive, MOGAD, and double-negative—each requiring tailored diagnostic and treatment approaches.
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The Challenge of Treating Fatigue in Multiple Sclerosis: Anthony Feinstein, MPhil, PhD, FRCPThe professor of psychiatry at the University of Toronto discussed the various medications for multiple sclerosis fatigue that have been tested but ultimately fail to outperform placebo. [WATCH TIME: 4 minutes]
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Challenges in Identifying Optimal Candidates for Muscular Dystrophy Gene Therapies: Melissa Spencer, PhDThe professor in residence at UCLA Health discussed the critical considerations when deciding appropriate patients for gene therapies, specifically AAV vectors, in treating muscular dystrophies. [WATCH TIME: 4 minutes]
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Emphasizing Patient Conversations and Treatment Opportunities for Seizure Management: Danielle Becker, MD, MS, FAESThe division director of epilepsy and associate professor of neurology at The Ohio State University Wexner Medical Center talked about the impact of ongoing seizures in patients with drug-resistant epilepsy and the importance of education for emerging opportunities in epilepsy care. [WATCH TIME: 3 minutes]
Latest:
The Complexity of Immune Cell Interactions and Potential Treatments for MS: Jenn Orthmann-Murphy, MD, PhDThe assistant professor of neurology in the Perelman School of Medicine at University of Pennsylvania talked about her presentation at CMSC 2024 on the complex interactions of immune cells in multiple sclerosis. [WATCH TIME: 6 minutes]
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Understanding Headache Essentials for General Neurologists: Susan W. Broner, MDThe medical director of the Weill Cornell Medicine Headache Program discussed key essential knowledge on the diagnosis, treatment, and pathophysiology of different headache types. [WATCH TIME: 6 minutes]
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Future Research on the Pathogenesis of COVID-19, Cognitive Changes: Joanna Hellmuth, MD, MSThe cognitive neurologist at the University of California San Francisco discussed the need to continue research on why patients develop cognitive changes following COVID-19 infection and how clinicians can care for them. [WATCH TIME: 4 minutes]
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Mitochondrial Molecules Linking to Alzheimer Disease Disparities in Gender: Betty Bigio, PhD; Carla Nasca, PhDA duo of experts from NYU Grossman School of Medicine talked about a new study that identified deficiencies in acetyl-L-carnitine and free carnitine as potential blood biomarkers for Alzheimer disease. [WATCH TIME: 5 minutes]
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Closing Thoughts on 2024 AUPN Annual MeetingThe meeting with the American Neurologic Association fosters collaboration, networking, and joint sessions, enhancing knowledge sharing among academic neurologists.
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Resources for Sleep DisordersDrs C. Michael Gibson, Ashgan A. Elshinawy, and Nathaniel F. Watson share resources for the treatment of sleep disorders.
