Opinion|Videos|January 7, 2025

Managing Disease Progression in MS: Changing Treatments and Clinician Advice

Author(s)Gabriel Pardo, MD, FAAN
Martin Belkin, DO

Panelists discuss how in multiple sclerosis (MS) treatment, clinicians must strategically evaluate disease progression, considering within-class or mechanism-of-action switches. Comprehensive monitoring, personalized approaches, and proactive management are crucial for optimizing patient outcomes and minimizing long-term neurological disability.

Video content above is prompted by the following:

In cases where a patient continues to show disease progression on a high-efficacy therapy, what is your approach to changing treatment? When would you recommend switching within class and when to a different mechanism of action?
In closing, what advice would you like to share with clinicians who are taking care of patients with MS?

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