Authors
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Shaun Hussain, MD, MS: Exploring the Connection Between Autism and Infantile SpasmsThe director of Infantile Spasms Program at UCLA Mattel Children’s Hospital discussed why learning more about patients with infantile spasms may lead to further breakthroughs on the origins of autism spectrum disorder.
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Treatment Challenges for Migraine During Pregnancy: Brian Grosberg, MD, FAHSThe medical director of the Hartford healthcare Headache Center in Connecticut discussed the significance of findings from a study assessing migraine during pregnancy. [WATCH TIME: 4 minutes]
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Jerome Engel, Jr., MD, PhD on Referring Patients to Epilepsy CentersThe Director of the UCLA Seizure Disorder Center explained the importance of referring patients with seizures to epilepsy centers.
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Shai Efrati, MD: Assessing Hyperbaric Oxygen Therapy for NeurodegenerationThe director of the Sagol Center for Hyperbaric Medicine and Research at Yitzhak Shamir Medical Center offers takeaways on hyperbaric oxygen therapy.
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Managing Psychosis in Parkinson Disease: Challenges and OpportunitiesAlthough the indication of pimavanserin has provided some relief, more work remains to improve how physicians diagnose, treat, and manage psychosis symptoms.
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Bruton Tyrosine Kinase Inhibitors: A New Hope for the Management of Progression in MS?Several therapies are progressing through the development pipeline and have shown promising data, setting up the multiple sclerosis treatment toolbox for possible expansion in coming years.
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Thomas Leist, MD: Resetting the Immune System With CladribineThe director of the Comprehensive Multiple Sclerosis Center at Thomas Jefferson University discussed the concept of lymphocyte depletion to reset the immune system.
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Postictal Generalized EEG Suppression as a Biomarker for SUDEP: Nancy R. Foldvary-Schaefer, DO, FAANThe director of the Sleep Disorders Center and staff in the Epilepsy Center at Cleveland Clinic discussed how additional sensors in seizure monitoring for patients with epilepsy may help better manage the risk of SUDEP. [WATCH TIME: 3 minutes]
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Early Treatment Response and Safety Profile of AXS-05 in Phase 3 ACCORD Trial: Anton P. Porsteinsson, MDThe director of the Alzheimer's Disease Care, Research and Education Program at the University of Rochester discussed treatment response and safety findings from the phase 3 ACCORD study assessing AXS-05 for agitation in Alzheimer disease. [WATCH TIME: 6 minutes]
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Generational Perspective in Multiple Sclerosis CareDr Krieger, Dr Brandstadter, and Dr Lublin discuss the advances made in recognizing and managing multiple sclerosis over the last few decades and the challenges that remain.
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Downstream Impacts of Undiagnosed Lennox-Gastaut Syndrome: Scott Perry, MDThe head of neurosciences at the Jane and John Justin Neurosciences Center of Cook Children’s Medical Center detailed some of consequences of undiagnosed or misdiagnosed LGS, and how it may impact long-term care for eligible patients. [WATCH TIME: 4 minutes]
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Richard Rudick, MD: The CogEval App in Clinical PracticeThe goal of the free application is to make cognitive assessments routine in multiple sclerosis treatment.
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Isabelle Lambert, MD: Spike, Spindle Frequency in Hippocampus During NREM Affect Long-Term MemoryImpairment of physiological spindle activity in the hippocampus during NREM sleep by interictal epileptic activities may have negative consequences on long-term memory consolidation.
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Annette Langer-Gould, MD, PhD: Lowering Postpartum MS Relapse Rates With BreastfeedingThe regional lead in clinical and translational neuroscience at Kaiser Permanente discussed subgroup findings from a study of pregnancy in women with MS which suggested that breastfeeding in the postpartum period can drastically decrease the risk of disease relapse.
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Partnering Clinicians With Parents as a Motivator for Pediatric Epilepsy Research: Zachary Grinspan, MD, MSThe pediatric epilepsy specialist at Weill Cornell Medicine in New York City spoke on how meetings such as the 2022 AES Conference bring clinicians together as well as how parents motivate them to advance pediatric epilepsy research. [WATCH TIME: 6 minutes]
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Jeffrey L. Cummings, MD, ScD: Optimal Therapeutic Targets for Addressing Alzheimer DiseaseThe director emeritus of the Cleveland Clinic Lou Ruvo Center for Brain Health and vice chair of the department of brain health at the University of Nevada Las Vegas spoke about therapies under investigation for the treatment of Alzheimer disease.
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Eva Winnebeck, PhD: Temporal Dynamics of SleepThe postdoctoral scientist spoke about an actimetry-based method studying the clinical relevance of temporal dynamics of sleep to make the dynamics easily quantifiable in everyday context.
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Aducanumab's Unlikely Road to the FDA: Is Approval Imminent?Recent news that the FDA has granted the fastest possible review for Biogen’s Alzheimer disease treatment aducanumab may be indicative of the agency’s increasing confidence in the drug.
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Analyzing Phase 2 CALLIPER Trial of IMU-838 for Progressive MS: Robert J. Fox, MDThe staff neurologist at the Mellen Center for Multiple Sclerosis at Cleveland Clinic talked about findings from an interim analysis of the phase 2 CALLIPER trial assessing vidofludimus calcium in progressive multiple sclerosis. [WATCH TIME: 4 minutes]
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The Changing Landscape of Preventative Migraine TreatmentsA panel of expert neurologists shares advice for community neurologists on preventive migraine treatment and exciting therapies to look forward to.
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Future Improvements in the Management of NarcolepsyExpert neurologists discuss advancements in the management of narcolepsy including new drug formulations and provide take-home messages for how to improve diagnosis and treatment in the future.
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Using Prior Success to Improve Alzheimer Trials, Drug Development: Jeffrey Cummings, MD, ScDThe director of the Chambers-Grundy Center for Transformative Neuroscience at the University of Nevada, Las Vegas discussed how the momentum gained within the Alzheimer community can springboard success going forward. [WATCH TIME: 4 minutes]
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Gill Livingston, MBChB, MD: Challenges of Sleep Difficulties in People Living with DementiaLivingston spoke to a number of topics in the dementia space, including the challenges clinicians face and her hope for the future.
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Raymond S. Turner, MD, PhD: Safety Results for Nilotinib in AlzheimerThe director of the Memory Disorders Program and professor of neurology at Georgetown University Medical Center detailed the phase 2 study findings of nilotinib in patients with Alzheimer disease.
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What You Need to Know About Amantadine for Parkinson DiseaseThis guide includes everything you need to know about amantadine (Osmolex ER, Osmotica Pharmaceuticals) for the treatment of Parkinson disease and drug-induced extrapyramidal reactions in adults.
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Pouya Ghaemmaghami, PhD: Predicted Gene Expression and the Association with Sleep MacrostructurePreliminary results show that the whole genome information can be used to assess the association between predicted gene expression in different parts of the brain and sleep, suggesting where brain genes are expressed matter for variability in sleep.
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Eyiyemisi Damisah, MD: Additional Insights Into Cell DeathThe assistant professor of neurosurgery at Yale School of Medicine discussed what doors have been opened by a recent study of the cell death process she and colleagues conducted.
