Authors
Latest:
David Llewellyn, PhD: The Impact of Lifestyle Factors on Genetic Risk in DementiaThe associate professor of neuroepidemiology and digital health spoke about the importance of findings from an observational study which showed that adherence to a healthy lifestyle can offset the genetic risk for dementia.
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David Leppert, MD: Building a Foundation for Neurofilament LightThe therapeutic head of neuroinflammation and pain at Novartis spoke about his desire to work to a point where physicians can use NfL to monitor disease activity, make therapeutic decisions, and give perspective to patients.
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The Progress Made in Stem Cell Therapy, Regenerative Medicine: Peter J. McAllister, MD, FAANThe medical director and chief medical officer of the New England Center for Neurology and Headache discussed notable data from the STEMTRA trial, and the progress made in the field of regenerative medicine. [WATCH TIME: 2 minutes]
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Sigma-1 Agonists Offer Combination Approach to Dementia SymptomsResearch from the past decade suggests that sigma-1 receptors and their encoding gene, SIGMAR1, together act as a therapeutic target for patients with dementia.
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Ian Miller, MD: Adapting AAV Gene Therapy for SCN1A-Positive EpilepsyThe medical director of the Comprehensive Epilepsy Clinic at Nicklaus Children’s Hospital discusses his early stage gene therapy trial for Dravet syndrome.
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Early High-Efficacy TreatmentJames Stankiewicz, MD, provides an overview of the burden of multiple sclerosis and discusses early, high-efficacy treatment of the disease.
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Peter Calabresi, MD: Utilizing A Uniform Biomarker AssayFor the director of the Johns Hopkins Multiple Sclerosis Center, a biomarker is perhaps only as useful as the clinician community’s ability to read out its measurements.
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Robert S. Fisher, MD, PhD: Exploring Unanswered Questions in EpilepsyThe Director of the Stanford Epilepsy Center discussed the work that’s left to be done in the field of epilepsy.
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Geoff Kerchner, MD, PhD: Phase III Trials of Crenezumab in Treatment of Prodromal to Mild AlzheimerData back a 4-fold higher dose of crenezumab in the CREAD 1 and CREAD 2 trials than used in phase II.
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Targeting the NF-kB Pathway in Duchenne Muscular DystrophyAn in-depth analysis of the genetics of DMD and disease modifiers such as the NF-kB pathway in patients with Duchenne muscular dystrophy.
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Daniel M. Goldenholz, MD, PhD: Assessing the Risk for SUDEPThe instructor in neurology at Beth Israel Deaconess Medical Center spoke about what clinicians can do right now to mitigate the risk of SUDEP and the myriad of options for them to utilize.
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World Alzheimer Day 2019: Key Takeaways From Leaders in Alzheimer Disease and DementiaIn recognition of World Alzheimer Day, experts in Alzheimer disease and dementia share insight from the latest Alzheimer Disease International's yearly World Alzheimer Report.
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Krista Lanctot, PhD: Managing Patients with AgitationLanctôt advised ruling out any possible underlying medical conditions that could be causing it, including pain, as well as starting with any non-pharmacologic interventions.
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Dina Katabi, PhD: Biosensors for Measuring Disease Activity in MS and Other Neurological DisordersThe Andrew & Erna Viterbi Professor of Electrical Engineering and Computer Science at MIT spoke about a new way of continuous monitoring for patients with MS and neurodegenerative disorders, discovering changes in quality of life and new biomarkers.
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Role of Combination Therapies in SMA ManagementJohn Brandsema, MD, and Julie Parsons, MD, review the evolution of combination therapy in clinical practice for the management of SMA.
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Screening for Alzheimer Disease: Facilitating an Early Diagnosis for Prompt InterventionIn this episode of MEDcast, expert geriatric psychiatrists explore the urgent need for effective diagnostic methods that can detect Alzheimer’s disease at an early stage. We will discuss blood-based biomarkers and other advancements that can help screen Alzheimer’s disease non-invasively and early in the disease course.
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State of Migraine Care and Therapeutics: Richard B. Lipton, MDThe director of the Montefiore Headache Center provided an overview of the recent advances in migraine medications and how it has translated to improved care. [WATCH TIME: 2 minutes]
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Moving Beyond Symptom Management, Using Antiseizure Medicines and Disease Modifying Therapies: Jacqueline French, MDThe professor of neurology at NYU Grossman School of Medicine and chief medical officer of the Epilepsy Foundation spoke about her talk on new treatments for drug resistant epilepsy given at the 2023 AAN Annual Meeting. [WATCH TIME: 6 minutes]
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Improving MS Care Through Innovative Trial Designs: Daniel Ontaneda, MD, PhDFollowing the 2024 ACTRIMS Forum, the associate professor of neurology at the Cleveland Clinic Lerner College of Medicine provided insight on the need to build creative trials for multiple sclerosis treatments. [WATCH TIME: 3 minutes]
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Antje Bischof, MD: Understanding Vasculitic NeuropathyThe postdoctoral scholar at the University of California San Francisco discussed the findings from her study that gives comprehensive insight into prevalence and organ associations of vasculitic neuropathy.
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Treating Narcolepsy in PregnancySleep medicine experts discuss the treatment of narcolepsy in pregnancy.
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Glenn Wylie, DPhil: The Future of Real-Time NeurofeedbackThe director of the Rocco Ortenzio Neuroimaging Center at Kessler Foundation spoke about the future of functional MRI in providing real-time neurofeedback, and how it might be incorporated as an end point in clinical trials.
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Erin Conrad, MD: Identifying the Seizure Onset ZoneThe epilepsy fellow at the hospital of the University of Pennsylvania detailed why locating the seizure onset zone plays a crucial role in successful epilepsy surgery.
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Fred Rincon, MD, MSc : Expanding Stroke Treatment Outside of NeurologyThe chief of cerebrovascular disease at Jefferson University Hospitals explains why teaching stroke protocol and using telemedicine can help close the gaps in stroke care.
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Targeting the Neonatal Fc Receptor in Myasthenia GravisUnderstanding the pathophysiology of myasthenia gravis is still being determined to this day, but the neonatal Fc receptor is emerging as a potential treatment.
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Exploring Synergistic Treatment Strategies for Migraine With Monoclonal Antibodies and Gepants: Stewart J Tepper, MDThe professor of neurology at the Geisel School of Medicine at Dartmouth talked about recent studies presented at the International Headache Congress on a potential migraine prevention treatment targeting pituitary adenylate cyclase activating polypeptide. [WATCH TIME: 5 minutes]
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Marie D'hooghe, MD, PhD: Pregnancy Plans for Patients With MSThe neurologist at the National MS Center and University Hospital, in Brussels, discussed the clinician mindset when treating women with MS who plan to get pregnant, and how patients using assistive reproductive treatments should be approached.
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Elizabeth Thiele, MD, PhD: CBD Shows Low-Dose Efficacy and Safety in TSCThe director of pediatric epilepsy and the Herscot Center for Tuberous Sclerosis Complex at Massachusetts General Hospital, and professor of neurology at Harvard Medical School spoke to the safety outcomes from GWPCARE6 and CBD’s low-dose efficacy.
