Authors
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Pouya Ghaemmaghami, PhD: Predicted Gene Expression and the Association with Sleep MacrostructurePreliminary results show that the whole genome information can be used to assess the association between predicted gene expression in different parts of the brain and sleep, suggesting where brain genes are expressed matter for variability in sleep.
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Eyiyemisi Damisah, MD: Additional Insights Into Cell DeathThe assistant professor of neurosurgery at Yale School of Medicine discussed what doors have been opened by a recent study of the cell death process she and colleagues conducted.
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Shared Decision-Making in Multiple Sclerosis TreatmentAhmed Obeidat, MD, PhD, Riley Bove, MD, Stephen Krieger, MD, and Erin Longbrake, MD, PhD, talk about the need for shared decision-making in MS care.
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Treatment Gaps Among Elders With Generalized Epilepsy: Vineet Punia, MD, MSThe neurologist at Cleveland Clinic addressed aspects of care for elders with generalized epilepsy that need to be further researched.
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Expanding the Use of Seizure Apps for Epilepsy: Jessica Fesler, MD, MEdThe staff epileptologist at Cleveland Clinic’s Epilepsy Center discussed new untapped ways seizure apps could help patients with epilepsy. [WATCH TIME: 2 minutes]
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David Llewellyn, PhD: The Impact of Lifestyle Factors on Genetic Risk in DementiaThe associate professor of neuroepidemiology and digital health spoke about the importance of findings from an observational study which showed that adherence to a healthy lifestyle can offset the genetic risk for dementia.
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David Leppert, MD: Building a Foundation for Neurofilament LightThe therapeutic head of neuroinflammation and pain at Novartis spoke about his desire to work to a point where physicians can use NfL to monitor disease activity, make therapeutic decisions, and give perspective to patients.
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Introducing DaxibotulinumtoxinA-Ianm as a Treatment Option for Cervical Dystonia: Peter J. McAllister, MD, FAANThe chief medical officer of New England Center for Neurology and Headache talked about trends observed in the clinical practice with Daxxify, a long-acting botulinum toxin for patients with cervical dystonia. [WATCH TIME: 5 minutes]
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Sigma-1 Agonists Offer Combination Approach to Dementia SymptomsResearch from the past decade suggests that sigma-1 receptors and their encoding gene, SIGMAR1, together act as a therapeutic target for patients with dementia.
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Ian Miller, MD: Adapting AAV Gene Therapy for SCN1A-Positive EpilepsyThe medical director of the Comprehensive Epilepsy Clinic at Nicklaus Children’s Hospital discusses his early stage gene therapy trial for Dravet syndrome.
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Early High-Efficacy TreatmentJames Stankiewicz, MD, provides an overview of the burden of multiple sclerosis and discusses early, high-efficacy treatment of the disease.
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Peter Calabresi, MD: Utilizing A Uniform Biomarker AssayFor the director of the Johns Hopkins Multiple Sclerosis Center, a biomarker is perhaps only as useful as the clinician community’s ability to read out its measurements.
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Robert S. Fisher, MD, PhD: Exploring Unanswered Questions in EpilepsyThe Director of the Stanford Epilepsy Center discussed the work that’s left to be done in the field of epilepsy.
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Geoff Kerchner, MD, PhD: Phase III Trials of Crenezumab in Treatment of Prodromal to Mild AlzheimerData back a 4-fold higher dose of crenezumab in the CREAD 1 and CREAD 2 trials than used in phase II.
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Targeting the NF-kB Pathway in Duchenne Muscular DystrophyAn in-depth analysis of the genetics of DMD and disease modifiers such as the NF-kB pathway in patients with Duchenne muscular dystrophy.
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Daniel M. Goldenholz, MD, PhD: Assessing the Risk for SUDEPThe instructor in neurology at Beth Israel Deaconess Medical Center spoke about what clinicians can do right now to mitigate the risk of SUDEP and the myriad of options for them to utilize.
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World Alzheimer Day 2019: Key Takeaways From Leaders in Alzheimer Disease and DementiaIn recognition of World Alzheimer Day, experts in Alzheimer disease and dementia share insight from the latest Alzheimer Disease International's yearly World Alzheimer Report.
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Understanding Clinical Predictors of Response to Nabilone in Alzheimer AgitationKrista L. Lanctôt, PhD, professor of psychiatry and pharmacology at the University of Toronto, talked about findings from a recent post hoc analysis presented at CTAD 2024 on nabilone for agitation in Alzheimer disease.
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Dina Katabi, PhD: Biosensors for Measuring Disease Activity in MS and Other Neurological DisordersThe Andrew & Erna Viterbi Professor of Electrical Engineering and Computer Science at MIT spoke about a new way of continuous monitoring for patients with MS and neurodegenerative disorders, discovering changes in quality of life and new biomarkers.
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Screening for Alzheimer Disease: Facilitating an Early Diagnosis for Prompt InterventionIn this episode of MEDcast, expert geriatric psychiatrists explore the urgent need for effective diagnostic methods that can detect Alzheimer’s disease at an early stage. We will discuss blood-based biomarkers and other advancements that can help screen Alzheimer’s disease non-invasively and early in the disease course.
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Safety and Efficacy Considerations of Newly Approved Combination Therapy for Acute Migraine: Richard B. Lipton, MDThe director of the Montefiore Headache Center at Albert Einstein College of Medicine provided an overview of the drug profile for the recently approved migraine treatment AXS-07. [WATCH TIME: 3 minutes]
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The Female Leaders Who Shaped an Epilepsy Icon: Reflections From Jacqueline A. French, MDJacqueline A. French, MD, a professor of neurology at the NYU Grossman School of Medicine, provided clinical perspectives on her experiences and career growth in neurology amid National Women Physicians Day.
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Revised McDonald Diagnostic Criteria Signals New Era in Multiple Sclerosis TreatmentThe 2024 revisions to the McDonald diagnostic criteria for multiple sclerosis (MS) mark a significant advancement in the early detection and diagnosis of the disease, with new biomarkers and a broadened scope that may lead to earlier intervention and improved patient outcomes.
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Antje Bischof, MD: Understanding Vasculitic NeuropathyThe postdoctoral scholar at the University of California San Francisco discussed the findings from her study that gives comprehensive insight into prevalence and organ associations of vasculitic neuropathy.
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Final Advice for Clinicians Treating NarcolepsyDrs Thorpy, Dogan, Doghramji, and Kushida share clinical pearls for primary care providers who are taking care of patients with narcolepsy.
