Opinion|Videos|June 5, 2025

Clinical Nurse Educators, Dosing Titrations to Manage Parkinson Disease

Author(s)Stuart H. Isaacson, MD, FAAN
Daniel E. Kremens, MD, JD

Panelists discuss how clinical nurse educators serve as vital partners in continuous subcutaneous apomorphine infusion management, providing patient education, troubleshooting technical issues, and collaborating with physicians on dosing titrations to optimize Parkinson disease symptom control.

Video content above is prompted by the following:

Role of Clinical Nurse Educators

Clinical Nurse Educator Roles:

Initial patient assessment and education
Device training and ongoing support
Regular monitoring and titration recommendations
First point of contact for troubleshooting
Liaison between patient and physician
Coordination of multidisciplinary care

Assistance With Dosing Titrations:

Systematic assessment of response using standardized tools
Remote monitoring and telehealth support
Implementation of physician-directed titration protocols
Identification of adverse effects requiring intervention
Documentation and communication of patient response patterns
Proactive management of common adverse effects
Guidance on infusion site rotation and care
Regular follow-up to ensure optimal adjustment

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