Dementia and Alzheimer Disease

Increased orexin in this disorder is associated with disease severity, total tau protein levels, sleep impairment, and cognitive deterioration.

Why ask patients to “spit in a cup”? Statistically significant protein differences have been found in Alzheimer disease saliva, and trends have been observed for Parkinson disease.

Does smell identification have any predictive value for later Alzheimer disease?

Cerebrospinal fluid biomarker assessment could conceivably become a part of routine clinical practice.

Try to stay current with the flood of published dementia studies these days and you may miss a few with human subjects. Here, a quick review of 2 non-animal analyses that might make you think differently in clinic tomorrow.

The notion that vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer disease was confirmed by the results of the largest study of its kind.

As clinicians, we can daily apply knowledge learned from a few patients with pure amnesia to patients we see often-those who have memory deficits, such as so-called Mild Cognitive Impairment and neurodegenerative diseases, such as Alzheimer's.

The remarkable coffee bean is associated with reduced prevalence of several diseases, including Parkinson disease, Alzheimer disease, cancer, cardiovascular disease, and diabetes.

Here: an update on the current state of CSF fluid-borne markers for Alzheimer disease and what they may portend.

The chair of Allegheny Health Network’s Neurosciences Institute discussed a groundbreaking phase 3 trial evaluating the safety and efficacy of deep brain stimulation in patients with Alzheimer disease. [WATCH TIME: 5 minutes]