The NeurologyLive® epilepsy clinical focus page provides information, podcasts, videos, and news about the latest FDA actions, clinical guideline updates, study and clinical trial findings, and interviews with physicians related to epilepsy and related epileptic conditions, including Lennox-Gastaut syndrome, Dravet syndrome, tuberous sclerosis complex, focal seizures, nonmotor seizures, and more.
August 26th 2025
Spanning across the United Kingdom, the United States, European Union, and Japan, the global phase 3 EMPEROR study of zorevunersen is expected to have data readout by the end of 2027.
How Surgical Interventions Improve Survival Rate in Pediatric Epilepsy: Sandi K. Lam, MD, MBA
December 4th 2023The division chief of pediatric neurosurgery at Ann & Robert H. Lurie Children's Hospital of Chicago talked about findings from a recently published study on long-term survival of pediatric patients with drug-resistant epilepsy which was presented at AES 2023. [WATCH TIME: 6 minutes]
The Persistent Challenge of Epilepsy Treatment Through the Ages: Louis Ferrari, RPh, MBA
December 3rd 2023The vice president of medical affairs at SK Life Science discussed how epilepsy remains a formidable challenge in the development of effective therapies to achieve seizure freedom. [WATCH TIME: 5 minutes]
Embracing New Approaches to Seizure Control Beyond Surgery: Gregory Krauss, MD
December 3rd 2023The professor of neurology at Johns Hopkins University School of Medicine discussed the traditional view of epilepsy treatment and how the paradigm has shifted to provide new treatments to achieve seizure freedom for drug-resistant patients. [WATCH TIME: 5 minutes]
Adjusting Antiseizure Medication Dosages Improves Retention of Cenobamate
December 2nd 2023In a recent post hoc analysis of the Study C021 trial, findings support the idea that early adjustments to concomitant antiseizure medications enhance the retention of cenobamate, an FDA-approved treatment for focal seizures.
A Paradigm Shift in Preventing Drug-Resistant Epilepsy: Pavel Klein, MD
December 1st 2023The director of the Mid-Atlantic Epilepsy & Sleep Center and adjunct associate professor of neurology at George Washington University discussed the advancements in epilepsy research, especially for drug-resistant epilepsy, to be presented at AES 2023. [WATCH TIME: 4 minutes]
Exploring the Hidden Burdens of Persistent Seizures for Patients: Danielle Becker, MD, MS, FAES
December 1st 2023The division director of epilepsy and associate professor of neurology at The Ohio State University Wexner Medical Center discussed the profound repercussion of ongoing seizures for patients with epilepsy which is to be presented at AES 2023 in SK Life Science’s symposium. [WATCH TIME: 5 minutes]
FDA Warns of Serious Adverse Effects for Using Levetiracetam and Clobazam in Epilepsy
November 28th 2023In a new announcement, the FDA warns patients to immediately seek out medical attention if unexplained rash, fever, or swollen lymph nodes develop when using the antiseizure medications levetiracetam and clobazam.
New Frontiers in the Prevention of Seizures, Gene Therapy in Epilepsy: William Gallentine, DO
November 28th 2023The interim chief of pediatric neurology at Stanford Medicine Children’s Health discussed progress in preventing seizures among patients with epilepsy, the potential for gene-targeted therapies, and the importance of localizing where seizures are coming from. [WATCH TIME: 5 minutes]
NRTX-1001 Shows Seizure Suppression in Preclinical Drug-Resistant Focal Epilepsy Models
November 27th 2023Neurona Therapeutics’ NRTX-1001, a regenerative neural cell therapy derived from human stem cells, showed promise in potentially suppressing seizures in patients with drug-resistant mesial temporal lobe epilepsy.
Study Reveals Association Between Amygdala Region and Persistent Breathing Loss Following Seizures
November 22nd 2023In a recently published study, investigators have identified a part of the brain that may be associated with breathing failure following a seizure in patients with severe epilepsy that cannot be managed with treatment.
Effectiveness of Midazolam for Seizure Cluster Management: Kamil Detyniecki, MD
November 21st 2023The associate professor of clinical neurology at the University of Miami Miller School of Medicine talked about findings from a recent post hoc analysis assessing the FDA-approved treatment of midazolam for seizure clusters. [WATCH TIME: 3 minutes]
Identifying the Right Candidate for Epilepsy Surgery: William Gallentine, DO
November 20th 2023The interim chief of pediatric neurology at Stanford Medicine Children’s Health provided insight on advances the screening for epilepsy surgery and the factors that pediatric neurologists should consider. [WATCH TIME: 5 minutes]