The NeurologyLive® epilepsy clinical focus page provides information, podcasts, videos, and news about the latest FDA actions, clinical guideline updates, study and clinical trial findings, and interviews with physicians related to epilepsy and related epileptic conditions, including Lennox-Gastaut syndrome, Dravet syndrome, tuberous sclerosis complex, focal seizures, nonmotor seizures, and more.
August 26th 2025
Spanning across the United Kingdom, the United States, European Union, and Japan, the global phase 3 EMPEROR study of zorevunersen is expected to have data readout by the end of 2027.
Improving Developmental Epileptic Encephalopathy Treatment With Soticlestat
October 18th 2019The director of pediatric epilepsy at Northeast Regional Epilepsy Group and co-director of epileptology at Hackensack University Medical Center provided context to these findings to explain how soticlestat can address challenges in developmental epileptic encephalopathies, as well as what may be next in its advancement.
Soticlestat Shows Promise for Developmental Epileptic Encephalopathies
October 17th 2019The director of pediatric epilepsy at Northeast Regional Epilepsy Group and co-director of epileptology at Hackensack University Medical Center spoke about soticlestat and what can be gleaned from data thus far.
The Critical Need to Monitor Post-Epilepsy Surgery Quality of Life
October 17th 2019Recent study results suggest that relative seizure reduction is an equivalent predictor of post-surgery quality of life in epilepsy to seizure freedom. Study author Lara Jehi, MD, offered insight into the value of these data.
Post-Epilepsy Surgery Quality of Life Can Be Predicted With Relative Seizure Reduction
October 16th 2019Relative seizure reduction was as equally strong a predictor of patient quality of life after epilepsy surgery as seizure freedom in a recent study, with absolute reduction proving to be the worst model surveyed.
Zogenix Resubmits Fenfluramine NDA in Dravet Syndrome
September 26th 2019Following the receipt of a refusal to file letter from the FDA, Zogenix has resubmitted its application for fenfluramine hydrochloride (Fintepla), seeking approval for the treatment of seizures associated with Dravet syndrome.
Danielle Andrade, MD, MSc: Communicating and Network Building in Epilepsy Care
September 24th 2019The professor of medicine, neurology, at the University of Toronto shared insight into the importance of communication and a good network of physicians to an adult neurologist caring for patients with epilepsy.
Danielle Andrade, MD, MSc: Education for Adult Neurologists on Pediatric-Onset Epilepsies
September 19th 2019The professor of medicine, neurology, at the University of Toronto discussed the best ways for adult neurologists to ensure a smooth transition of care for patients with epilepsy entering their care.
Danielle Andrade, MD, MSc: Ensuring Smooth Transitions to Adult Epilepsy Care
September 18th 2019The professor of medicine, neurology, at the University of Toronto discussed the best ways for pediatric neurologists to ensure a smooth transition of care for patients with epilepsy who are leaving the pediatric system.
R. Edward Hogan, MD: Clinician Takeaways for Using Diazepam Nasal Spray
September 17th 2019The director of the adult epilepsy center at Washington University in St. Louis discussed the takeaways for clinicians regarding the use of intranasal diazepam as a treatment for runs of seizures in patients with refractory epilepsy.
Exploring Alternative AED Dosing to Boost Treatment Adherence
September 12th 2019Rodney Allan Radtke, MD, professor of neurology at Duke University School of Medicine in Durham, North Carolina, discussed some of the new therapeutic options available to help improve tolerance and adherence challenges that clinicians commonly face in epilepsy practice.
Danielle Andrade, MD, MSc: Coordinating Epilepsy Care Transition Between Physicians
September 11th 2019The professor of medicine, neurology, at the University of Toronto discussed the need for physicians to work together while transitioning patients with epilepsy—who may have any number of comorbidities—from pediatric care to adult care.
R. Edward Hogan, MD: Diazepam Nasal Spray Offers Benefits and Long-Term Safety
September 10th 2019The director of the adult epilepsy center at Washington University in St. Louis spoke about the use of diazepam nasal spray in patients with epilepsy ­and detailed the advantages it offers these patients and their physicians.
Danielle Andrade, MD, MSc: Transitioning Patients With Epilepsy to Adult Care
September 10th 2019The professor of medicine, neurology, at the University of Toronto spoke to the hurdles faced by both pediatric and adult neurologists when transitioning a patient with epilepsy from childhood care to adult care.
Exploring Alternative AED Dosing to Boost Treatment Adherence
August 26th 2019Rodney Allan Radtke, MD, professor of neurology at Duke University School of Medicine in Durham, North Carolina, discussed some of the new therapeutic options available to help improve tolerance and adherence challenges that clinicians commonly face in epilepsy practice.
The Symbiotic Relationship of Artificial Intelligence and Neurology
August 18th 2019The associate chief of the MS division and professor of neurology at the University of Pennsylvania described the relationship between artificial intelligence and medicine, and how he sees it evolving in the future.
Research is Key to Finding a Place for CBD in Epilepsy Treatment
August 16th 2019The pediatric neurologist and epilepsy specialist at Children’s Hospital Colorado spoke about patient interest in cannabidiol after the FDA approval of Epidiolex, and what remains to be done to perfect its use in epilepsy.