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AES
Treating Epilepsy: Key Takeaways From AES 2020
January 20, 2021
Trevor J. Resnick, MD, reviews data presented at the American Epilepsy Society (AES) Annual Meeting 2020.
Pavel Klein, MD: Determining Likelihood of Efficacy and AEs in Patient Populations
January 19, 2021
The director of the Mid-Atlantic Epilepsy and Sleep Center discussed his team’s investigations into predicting responders and adverse events.
William Rosenfeld, MD: Reducing Concomitant ASM Dosages for Focal Seizures
January 17, 2021
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed the different medications that cenobamate was used with.
Cenobamate’s Efficacy in Seizure Freedom and Decreasing Concomitant Medication Use
January 14, 2021
William Rosenfeld, MD, discusses the decreases his team observed in concomitant medication use with cenobamate in patients with focal seizures.
Pavel Klein, MD: Finding the Right AEDs for Patients With Epilepsy
January 09, 2021
The director of the Mid-Atlantic Epilepsy and Sleep Center urged physicians to catch refractory epilepsy early and look for the most efficacious treatments for their patients.
REM Not Correlated With Increased Risk of SUDEP
January 09, 2021
Although the percentage of total seizures arising from REM was low, it is notable that 2 out of 26 patients (7.7%) had REM-onset seizures.
William Rosenfeld, MD: Decreasing Concomitant ASM Use With Cenobamate for Epilepsy
January 08, 2021
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team saw a roughly 25% decrease in the mean use of concomitant ASMs.
Pavel Klein, MD: Brivaracetam Efficacy Inversely Proportional to Number of Lifetime AEDs
January 03, 2021
The director of the Mid-Atlantic Epilepsy and Sleep Center urged physicians to try and find the right medications for their patients as early as possible.
William Rosenfeld, MD: Finding Ideal Combinations of Cenobamate and Concurrent ASMs
January 01, 2021
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team succeeded at titrating cenobamate early in the study.
Pavel Klein, MD: Efficacy of Brivaracetam on Refractory Epilepsy
December 31, 2020
The director of the Mid-Atlantic Epilepsy and Sleep Center urged physicians to actively look for new medications for patients to try.
William Rosenfeld, MD: Balancing Cenobamate and Concomitant ASMs
December 29, 2020
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team studied the interactions of ASMs and cenobamate.
Pavel Klein, MD: Challenges of Treating Drug-Resistant Epilepsy
December 28, 2020
The director of the Mid-Atlantic Epilepsy and Sleep Center also noted how serious adverse effects from treatment can be detrimental to patients’ lives.
William Rosenfeld, MD: Observing Interactions of Cenobamate and Concomitant ASMs
December 25, 2020
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team worked to reduce deleterious ASM interactions.
Pavel Klein, MD: Brivaracetam is Benign and Efficacious for Focal Seizures
December 24, 2020
The director of the Mid-Atlantic Epilepsy and Sleep Center also urged physicians to not give up on the search for effective AEDs for their patients.
Kelly Knupp, MD: Treatment Landscape for Lennox-Gastaut Syndrome
December 19, 2020
The pediatric neurologist and epilepsy specialist at Colorado Children’s Hospital discussed how the treatment landscape for patients with Lennox-Gastaut syndrome could alter if fenfluramine is approved.
William Rosenfeld, MD: Greater Efficacy of Cenobamate With Fewer Concomitant ASMs
December 18, 2020
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how patients with intractable epilepsy found cenobamate effective.
Christian Meisel, MD, PhD: Treatment Landscape for Seizure Forecasting Devices
December 16, 2020
The neurologist from Universitätsmedizin Berlin and Berlin Institute of Health provided his insight on the reasons for the limited number of FDA-approved seizure forecasting devices.
Transdermal CBD Efficacious in Children With Developmental and Epileptic Encephalopathies
December 16, 2020
Efficacy was observed in patients with DEEs such as West Syndrome, Lennox-Gastaut syndrome, and Dravet syndrome.
NeuroVoices: Eric Segal, MD, on Real World Use of Diazepam Nasal Spray
December 16, 2020
Eric Segal, MD, director of pediatric epilepsy, HMH Hackensack University Medical Center, detailed his study on diazepam nasal spray in patients with and without antiseizure medications.
Positive Fenfluramine Data in LGS Suggest an FDA Approval Is on the Horizon
December 12, 2020
Kelly Knupp, MD, pediatric neurologist and epilepsy specialist, Children’s Hospital Colorado, detailed the findings of fenfluramine in patients with Lennox-Gastaut syndrome and how it may shake up the treatment landscape.