The International Epilepsy Congress is put on annually by the International League Against Epilepsy and features a variety of experts in the care and management of epilepsy and seizure disorders.
Shift in Treatment Paradigm for Dravet Syndrome: Joseph Sullivan, MD
The director of the Pediatric Epilepsy Center at UCSF provided perspective on the advances in the treatment of Dravet syndrome, emerging research concepts in the field, and the influence of genetic testing. [WATCH TIME: 5 minutes]
NeuroVoices: Joseph Sullivan, MD, on Exploring Antisense Oligonucleotides for Dravet Syndrome, Rare Epilepsies
The director of the Pediatric Epilepsy Center at UCSF provided perspective on STK-001, a promising antisense oligonucleotide in development, and the shift in how Dravet syndrome is discussed and managed.
Antiseizure Therapy Fenfluramine Continues to Show Pronounced Benefits in Rare, Developmental Epilepsies
One meta-analysis featuring 8 studies showed that more than half of patients reported a 100% reduction in their generalized tonic-clonic seizures or tonic-clonic seizures.
Rapid Administration of Diazepam Results in Improved Seizure Cluster Cessation, Shorter Seizures
Treatment with diazepam nasal spray resulted in a statistically significant change in time between seizure clusters, potentially reflecting a beneficial effect of intermittent rescue therapy.
Early-Stage Findings of Ketogenic Agent CER-0001 in Infantile Spasms Warrant Further Investigation
Half of the treated individuals saw a reduction of more than 50% in the number and duration of epileptic spasms following treatment with CER-0001, a ketogenic therapy.
Anup Patel, MD: Transmitting Epilepsy Information Correctly
The associate professor of clinical pediatrics and neurology at Ohio State University and section chief of pediatric neurology at Nationwide Children’s Hospital stresses the importance of broadcasting correct information to the public concerning epilepsy.
Anup Patel, MD: The Realities of Cannabidiol Treatment for Epilepsy
The section chief of pediatric neurology at Nationwide Children’s Hospital discusses the realities parents face when exploring CBD to treat epilepsy.
Danielle Andrade, MD, MSc: Communicating and Network Building in Epilepsy Care
The professor of medicine, neurology, at the University of Toronto shared insight into the importance of communication and a good network of physicians to an adult neurologist caring for patients with epilepsy.
Danielle Andrade, MD, MSc: Education for Adult Neurologists on Pediatric-Onset Epilepsies
The professor of medicine, neurology, at the University of Toronto discussed the best ways for adult neurologists to ensure a smooth transition of care for patients with epilepsy entering their care.
Danielle Andrade, MD, MSc: Ensuring Smooth Transitions to Adult Epilepsy Care
The professor of medicine, neurology, at the University of Toronto discussed the best ways for pediatric neurologists to ensure a smooth transition of care for patients with epilepsy who are leaving the pediatric system.
Danielle Andrade, MD, MSc: Coordinating Epilepsy Care Transition Between Physicians
The professor of medicine, neurology, at the University of Toronto discussed the need for physicians to work together while transitioning patients with epilepsy—who may have any number of comorbidities—from pediatric care to adult care.
Danielle Andrade, MD, MSc: Transitioning Patients With Epilepsy to Adult Care
The professor of medicine, neurology, at the University of Toronto spoke to the hurdles faced by both pediatric and adult neurologists when transitioning a patient with epilepsy from childhood care to adult care.
The Impact of Noninvasive Epilepsy Interventions
The director of comprehensive epilepsy center and professor of neurology at Thomas Jefferson University spoke to the evolution of epilepsy interventions over the last decade and its effect on the level of care for patients.
Sarah Wilson, PhD: Long-Term Social Outcomes of Epilepsy Surgery
The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne discussed the results of a study she and colleagues conducted in which they mapped the long-term social outcomes of patient post-epilepsy surgery.
Sarah Wilson, PhD: Managing Post-Operative Patients With Epilepsy
The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne detailed how the transition from states of illness to wellness after epilepsy surgery can result not just in brain changes, but psychosocial challenges for patients.
Sarah Wilson, PhD: The Burden of Normality Post-Epilepsy Surgery
The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne spoke about what physicians need to provide to help patients through the adjustment period after epilepsy surgery.
Sarah Wilson, PhD: The Promise of Neurorehabilitation After Epilepsy Surgery
The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne discussed the early-stage research into neurorehabilitation post-epilepsy surgery, and the promise it might hold to address surgery’s long-term risks.
Michael Sperling, MD: Noninvasive Techniques in Epilepsy
The director of the Jefferson Comprehensive Epilepsy Center discussed what’s currently being developed in the treatment of epilepsy, as well as the emergence of different methods of stimulation and neuromodulation.
James W. Wheless, MD: Making Treatment Decisions in Epilepsy
The professor and chief of pediatric neurology at Le Bonheur Children’s Hospital and the University of Tennessee Health Science Center discussed the decision-making process for choosing interventions for patients with epilepsy, and how to keep patients adherent.
James W. Wheless, MD: The Consequences of Uncontrolled Epilepsy
The professor and chief of pediatric neurology at Le Bonheur Children’s Hospital and the University of Tennessee Health Science Center spoke about the concerns of uncontrolled epilepsy and how to determine if a patient requires more than one treatment for their epilepsy.
Kelly Knupp, MD: Increasing Patient Curiosity About CBD in Epilepsy
The pediatric neurologist and epilepsy specialist at Children’s Hospital Colorado discussed the popularity of cannabidiol from coverage in the media, and how she sees its use—and the understanding of it—evolving in the coming years.
Kelly Knupp, MD: Keeping Perspective on CBD for Pediatric Epilepsies
The pediatric neurologist and epilepsy specialist at Children’s Hospital Colorado spoke about the need to continue to research therapies once they’re approved to better understand their use, and how cannabidiol falls into this category.
Michael Sperling, MD: Surgical Advancements for Epilepsy
The director of the Jefferson Comprehensive Epilepsy Center spoke about the improvements that have come along with some of the surgical advancements in the treatment of epilepsy, specifically with laser interstitial thermal ablation.
Sharon Chiang, MD, PhD: Recording Seizures With Detection Technology
The neurology resident at the University of California San Francisco discussed how new wearable technology and electronic diaries have helped improve the understanding of seizure rhythmicity, and ultimately, epilepsy care.
Improving Epilepsy Care By Systematically Measuring Seizure Rhythmicity
In order to improve patient care in epilepsy, physicians need a more consistent and cohesive method of recording patient seizure activity. As wearables get more sensitive and specific, using them in tandem with electronic seizure diaries may help address the challenge.
Sharon Chiang, MD, PhD: The Usefulness of Seizure Diaries in Epilepsy
The neurology resident at the University of California San Francisco spoke about the role that seizure diaries can play in a patient’s peace of mind, as well as in the understanding of that patient’s response to a given treatment.
Preventive Treatment in Tuberous Sclerosis Complex Lowers Risk for Refractory Epilepsy
Patients whose EEG changes were monitored prior to onset of clinical seizures and who were given preventive therapy demonstrated a lower risk of epilepsy overall, especially drug-refractory.
Epileptogenic Zone, Epilepsy Duration, and Interictal Discharges Predict Postoperative Seizure Outcomes
A trio of predictors may help inform which patients may be candidates for resective surgery, as well as improve the postsurgical consideration for re-operation on those who experience disabling seizure recurrence.
Lara Jehi, MD: Epilepsy Treatment Algorithms as Personalized Medicine
The professor of neurology at Cleveland Clinic’s epilepsy center discussed how algorithms can better influence the personalization of medicine, not just in the field of epilepsy, but in medicine as a whole.
In Intractable Epilepsy, Rufinamide is Well-Tolerated and Effective
Data suggest that rufinamide is capable of aiding in the control and reduction of seizures, as well as the possible achievement of seizure-freedom in pediatric patients with genetic/metabolic, hypoxic-ischemic, structural, and other intractable epilepsies.
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