Latest Conference Coverage

Danny Eckert, PhD: Unlocking New Targets For Pharmacological Therapy In OSA

The identification of 3 key non-anatomical contributors to OSA has unlocked new potential pharmacotherapies, a major advance for the field.

Jan Hedner, MD, PhD: Current Therapeutic Landscape of Obstructive Sleep Apnea

Recent research has identified novel potential pathophysiological mechanisms that could potentially serve to subclassify various phenotypes in obstructive sleep apnea.

Eva Winnebeck, PhD: Movement Rhythms During Sleep

The actimetry-based method allows for easily quantifiable sleep dynamics in real life context, enabling large-scale clinical studies to investigate the complex temporal dynamics of sleep.

Krista Lanctot, PhD: Managing Patients with Agitation

Lanctôt advised ruling out any possible underlying medical conditions that could be causing it, including pain, as well as starting with any non-pharmacologic interventions.

Geert Mayer, MD: Safety, Efficacy of Solriamfetol for Excessive Sleepiness In Narcolepsy, OSA

Long-term maintenance of efficacy was demonstrated with solriamfetol for treatment of excessive sleepiness with narcolepsy or obstructive sleep apnea.

Irina Pikuleva, PhD: Activating CYP46A1 with Efavirenz

The Carl F. Asseff Professor of Ophthalmology and the Director of the Visual Sciences Research Center at Case Western Reserve University spoke about the beginnings of her work with efavirenz.

Geert Mayer, MD: Solriamfetol As Potential Therapy for Excessive Sleepiness in Narcolepsy, Obstructive Sleep Apnea

The neurologist and sleep specialist spoke about data from one of many studies investigating solriamfetol for treatment of narcolepsy and obstructive sleep apnea with remaining excessive daytime sleepiness.

Paul Newhouse, MD: Attacking Different Targets in Alzheimer

The Jim Turner Chair in Cognitive Disorders at the Vanderbilt University School of Medicine shared his feelings on the early phase treatments.

Daphne Chylinski: Arousals During Sleep Are Strongly Linked to Alzheimer Disease Pathophysiology

Chylinski spoke about the relationship between the increased number of arousals during sleep and the pathogenesis of Alzheimer disease.

Howard Fillit, MD: The Importance of Biomarkers for Alzheimer Disease

Fillit spoke about remaining need for additional biomarkers in Alzheimer, and what has been developed in recent years.

Krista Lanctot, PhD: Addressing Alzheimer Disease Agitation

The psychiatry and pharmacology professor at the University of Toronto and senior scientist at Sunnybrook Research Institute spoke about the use of cannabinoids to treat agitation in Alzheimer.

Irina Pikuleva, PhD: Using Efavirenz in Alzheimer Disease

The Carl F. Asseff Professor of Ophthalmology and the Director of the Visual Sciences Research Center at Case Western Reserve University further discussed the trial of efavirenz in AD.

Eugenia Trushina, PhD: Communication and Learning Through Collaboration

For the associate professor of neurology, learning, listening, and collaborating are the keys to improving the field of care.

Paul Newhouse, MD: Exploring VU319 in Alzheimer Disease

The Jim Turner Chair in Cognitive Disorders at the Vanderbilt University School of Medicine explained more about the molecule and the subsequent trial of it.

Howard Fillit, MD: Emphasizing Care in Alzheimer Disease

With a heavy focus on the need for new treatments in Alzheimer, there remains a need to ensure patients are cared for first and foremost.

Biomarker Research Required to Further Advance Alzheimer Drug Discovery

Novel biomarkers are being explored to help expedite the development of new treatments for Alzheimer disease.

Ronald Crystal, MD: Introducing Genetics into Alzheimer Disease

Could the introduction of gene therapies into the Alzheimer space be the beginning of a new era of treatment?

Eugenia Trushina, PhD: Mitochondria as a Therapeutic Target for Alzheimer

The associate professor of neurology at Mayo Clinic spoke about targeting mitochondria to treat neurologic disorders.

Howard Fillit, MD: Alzheimer Disease Drug Development Improvement

The ADDF's founding executive director and chief scientific officer spoke about the gains in clinical trials in the last 5 years.

Allogeneic Mesenchymal Stem Cells Under Exploration for Alzheimer Disease, Aging Frailty

Allogeneic mesenchymal stem cells manufactured by Longeveron are advancing through phase I and II clinical trials.

Ronald Crystal, MD: APOE2 Gene Therapy for Alzheimer Disease

The chairman of the Department of Genetic Medicine at Weill Cornell Medicine shared his experience with the therapy and its potential in the space.

Kelvin Tsoi, PhD: Combination Therapy, Monotherapy in Alzheimer Disease

After identifying and reviewing 76 randomized trials, combination therapy with memantine and AChEIs is confirmed to have no additional benefits over monotherapy.

Lutz Frolich, MD, PhD: Learning from Negative Trials

Lutz Frölich, MD, PhD, spoke about the importance of continuing with research in light of negative trials in Alzheimer disease.

James Hendrix, PhD: Progress and Challenges in the Alzheimer Space

Hendrix spoke to the challenges he and colleagues come across, as well as his hope for the promising future.

Dennis Selkoe, MD: Current Challenges in Alzheimer Disease and Hope for the Future

Selkoe spoke to a number of topics in the Alzheimer space, including the challenges in the field and his excitement for the future.

Lutz Frolich, MD, PhD: Collaboration Between Clinicians and Industry

Lutz Frölich, MD, PhD, discussed the imperativeness of collaboration between stakeholders—clinicians, pharmaceutical companies, researchers—in developing therapies for Alzheimer disease.

Nir Lipsman, MD, PhD: Innovations in Alzheimer Disease

The neurosurgeon from Sunnybrook Health Sciences Centre spoke about his excitement about where the medical community is at, at this point, in the understanding of Alzheimer disease.

Gill Livingston, MBChB, MD: Challenges of Sleep Difficulties in People Living with Dementia

Livingston spoke to a number of topics in the dementia space, including the challenges clinicians face and her hope for the future.

Lutz Frolich, MD, PhD: Tempering Expectations for Alzheimer Disease Advancements

The head of the Department for Geriatric Psychiatry, Central Institute of Mental Health talked about the biggest challenges facing medicine in treating and understanding Alzheimer disease.

Gill Livingston, MBChB, MD: Manual Based Intervention for Sleep Difficulties in Dementia

DREAMS-START demonstrates that a manual-based psychological treatment for sleep disorders in dementia is feasible and acceptable.