MOVEMENT DISORDERS

NeurologyLive's Movement Disorders Clinical Focus page focuses on the latest news and research across a variety of movement disorders, such as Parkinson disease, Tardive dyskinesia, Huntington disease, and tremors.

Insight from Asa Abeliovich, MD, PhD

Parkinson Disease Gene Therapy PR001 Granted Fast Track Designation

A phase 1/2 clinical trial is expected to be initiated in the second half of 2019.

Rodolfo Savica, MD, PhD: Dyskinesias in Atypical Parkinsonism

The associate professor of neurology at Mayo Clinic spoke about the findings of a population-based cohort study seeking to investigate the incidence of levodopa-induced dyskinesia in atypical parkinsonism.

Exploring the VMAT2 Pathway in Tardive Dyskinesia

VMAT2, given its role in presynaptic packaging, storage, and release of dopamine, has emerged as a promising target for therapeutic interventions to manage movement disorders.

FDA Grants Fast Track Designation to ABO-202 AAV9 Gene Therapy for Batten Disease

Abeona Therapeutics is currently planning a phase 1/2 clinical trial to evaluate ABO-202 in Batten disease.

Deferiprone Slows PKAN Disease Progression, Marking An Important Step in Treatment

Despite the clinical benefit being limited, the slowing of pantothenate kinase-associated neurodegeneration disease progression—particularly in atypical cases—is a step toward developing a treatment for the orphan disease.

Exome Panel Promising for Diagnosing Epilepsy, Pamrevlumab for Duchenne Muscular Dystrophy Receives Orphan Drug Designation, Riluzole NDA Accepted for ALS

Guidelines for Pediatric Migraine Clinical Trial Design Released, FDA Grants AMT-130 Fast Track Designation for Huntington Disease, ZX008 Receives RFL for Dravet Syndrome

Siponimod Approved for SPMS, AVP-786 Phase 3 Results for Treatment of Agitation in Alzheimer-Related Dementia, and Mobile Technology for Care of Parkinson Disease

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About NeurologyLive's Movement Disorders Clinical Focus page:

The NeurologyLive Movement Disorder Clinical Focus center provides a source of up-to-date clinical information, with articles covering updates from the robust pipeline of novel therapies, and the newest data from all phases of clinical trials and studies in the space. It also serves as a hub of information and news from the upcoming and ongoing conferences and annual meetings hosted by neurological societies and associations on the latest advances in Parkinson disease, Tardive dyskinesia, Huntington disease, and more.

This resource includes a wealth of interviews with movement disorder specialists, and moderated Peer Exchange discussions about the best practices and key methods for treating complex cases, utilizing the newest therapies, examining the issues and challenges of treatment options, and much more.