NeurologyLive Peer Exchange

Stuart Isaacson, MD; Daniel Kremens, MD, JD; Jill Ostrem, MD; Robert Hauser, MD, MBA, and Rajesh Pahwa, MD discuss how emerging therapeutic strategies and personalized treatment plans are transforming the management of off fluctuations in Parkinson's Disease, offering patients improved symptom control and quality of life.

4 experts in this video

Fernando Pagan, MD; Jason Aldred, MD, FAAN; Maria Cristina Ospina, MD; and Rajeev Kumar, MD, discuss how to navigate the complexities of choosing the most effective pharmacological and nonpharmacological treatment regimens for patients with advanced Parkinson disease, considering the evolving challenges and needs as the disease progresses, the impact on quality of life, and the incorporation of emerging therapies such as continuous subcutaneous infusion systems.

4 KOLs are featured in this series

Nicholas J. Silvestri, MD, FAAN; Ali A. Habib, MD; Neelam Goyal, MD; and Katherine Ruzhansky, MD, MS, explore the multifaceted aspects of generalized myasthenia gravis, from its clinical presentation and diagnosis to emerging targeted therapies, emphasizing the importance of personalized treatment approaches, discussing recent clinical trial data, and addressing ongoing challenges in both adult and pediatric populations.

Four healthcare professionals highlight variation in spasticity presentation and examine options available for management of spasticity. They discuss use of intrathecal baclofen (ITB) for treatment of severe spasticity, candidate patients who are likely to most benefit from ITB use, challenges and recent data with ITB use.

In a panel discussion, multiple sclerosis (MS) experts Stephen Krieger, MD; Heidi Crayton, MD; Jacqueline Nicholas, MD, PhD; Patricia Coyle, MD, and Enrique Alvarez, MD, PhD, share their insights on current MS therapies, aspirations for guideline revisions, the importance of shared decision-making, and the role of medium-efficacy therapy in the management of mild-to-moderate MS.

5 KOLs in this panel

Lauren Elman, MD; Arun Varadhachary, MD, PhD; Thomas Crawford, MD; Julie Parsons, MD, and Crystal Proud, MD, provide valuable insights into the distinct clinical features of pediatric and adult SMA, the complex process of transitioning patients from pediatric to adult healthcare services, and the importance of effectively counseling patients on available treatment options and setting realistic expectations for treatment success.

In this program, experts in sleep medicine focus on the treatment and management of excessive daytime sleepiness in narcolepsy. Together, they discuss patient selection criteria for available treatment options and guidance on switching therapies in narcolepsy.

In an upcoming Peer Exchange program entitled “Dual-Orexin Receptor Antagonists for Treatment of Insomnia” Dr Paul Doghramji will moderate a conversation with physicians about this class of agents for treatment of insomnia and discuss other therapeutic advancements in the field.

Experts discuss Bruton's tyrosine kinase (BTK) inhibitors, which block the actions of B cells and may affect other cell types that can facilitate inflammation, recent key clinical data on BTK inhibitors in multiple sclerosis. and how to incorporate these novel agents into treatment plans once they become available.

Expert neurologists focus on generic disease-modifying therapies (DMTs) for relapsing-remitting multiple sclerosis (RRMS). They discuss the expected benefit of generic DMTs and use in clinical practice. The panelists also review clinical cases and discuss possible treatment plans.

An expert neurology panel discusses diagnosis and treatment of dyskinesia in patients with Parkinson’s Disease. They discuss challenges in treating dyskinesia and finding a balance between OFF episodes and ON time, and current and emerging treatment options available for dyskinesia treatment.

An expert Brazilian panel review the state of diagnosis and treatment of SMA, highlighting available treatments and factors that guide treatment selection.

Neurologistas e especialistas clínicos discutem diagnóstico e tratamento da Atrofia Muscular Espinhal (AME) na população pediátrica do Brasil. Eles destacam tratamentos disponíveis, pacientes ideais para cada tratamento, necessidades de monitoramento e importância do cuidado multidisciplinar no manejo da AME

A panel of experts in neurology discuss comorbidities in multiple sclerosis and the use of sphingosine 1-phosphate receptor modulators for treatment. They discuss data on sequencing of disease modifying therapies and challenges and their approaches to guiding patients through treatment discontinuations.

Expert neurologists discuss the impact of MS on the immune system and comment on the use of COVID-19 vaccines with MS treatment and the use of high efficacy therapies in MS.

In this Peer Exchange special edition, Scott Newsome, DO, leads a discussion with Alberto Ascherio, MD, DrPH; Anne Cross, MD; Avindra Nath, MD; and Michael Racke, MD, about the practical and clinical implications of a recently published novel longitudinal study, the first of its kind to draw a causal link between Epstein-Barr Virus and multiple sclerosis.

Jessica Ailani, MD; Bradley Torphy, MD; Sait Ashina, MD; Andrew C. Charles, MD; and Julio R. Vieira, MD, share expert approaches to the diagnosis and treatment of acute and preventive migraine and discuss key insights on the evolving treatment landscape.