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ALS Association

The ALS Association is the largest private funder of ALS research in the world. The Association funds global research collaborations, provides assistance for people with ALS and their families through our nationwide network of chapters and certified clinical care centers, and advocates for better public policies for people with ALS. The ALS Association builds hope and enhances quality of life while urgently searching for new treatments and a cure. For more information about The ALS Association, visit our website at www.als.org.

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Latest from ALS Association

Patient-Reported Outcomes Worsen as ALS Disease Progresses, Real-World Study Shows

November 04, 2022

Article

On King’s staging systems, ALSAQ-5 scores increased from 24.6 at stage 1 to 62.1 at stage 4, whereas for Milano-Torino Staging systems, patients’ ALSAQ-5 scores increased from 43.2 at stage 0 to 80.7 at stage 3.

The Significance of AMX0035 and a Fueled Hope for ALS

November 02, 2022

Article

Once thought nearly impossible to treat, ALS has seen another step of progress with the approval of AMX0035 and a future of potential therapeutics on the way.

Overcoming the Complexities With Gene Therapy in ALS: Anna Underhill, BS

August 18, 2022

Video

The postdoctoral researcher at King’s College London provided background on why gene therapies have not seen as much success in treating ALS, and the need for additional validation of genetic mutations. [WATCH TIME: 3 minutes]

Differences in the Genetic Mutations of ALS: Anna Underhill, BS

August 17, 2022

Video

The postdoctoral researcher at King’s College London provided insight on the immunologic differences between genes linked with ALS, and the important aspects to consider for gene-targeted therapies. [WATCH TIME: 3 minutes]

Therapeutic Potential of Targeting SARM1 in ALS: Anna Underhill, BS

August 15, 2022

Video

The postdoctoral researcher at King’s College London discussed the mechanistic role SARM1 gene mutations play in the development and progression of ALS. [WATCH TIME: 3 minutes]

Treating Familial ALS at the Source: The Introduction of Gene Therapies

July 20, 2022

Article

As scientific researchers continue to uncover new genetic links to amyotrophic lateral sclerosis, the rise of gene therapies to treat the neuromuscular disease will remain a development to watch in the coming years.