Opinion|Videos|May 13, 2024

Amyloid Cascade Hypothesis of Alzheimer’s Disease

Panelists delve into the amyloid cascade hypothesis of Alzheimer's disease and the ongoing debate surrounding it, discussing the presence and potential roles of Aβ monomers, oligomers, protofibrils, and amyloid plaques in patients with Alzheimer's disease.

What is the amyloid cascade hypothesis of Alzheimer’s disease?
- When are Aβ monomers, oligomers, protofibrils and amyloid plaques seen in patients with Alzheimer’s disease?
- What are the strengths and weaknesses of amyloid cascade hypothesis?

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