Preparing for a New Era in Alzheimer's Disease: Debating New Targeted Biomarkers and Therapeutic Approaches : Episode 4
Amyloid Cascade Hypothesis of Alzheimer’s Disease
Panelists delve into the amyloid cascade hypothesis of Alzheimer's disease and the ongoing debate surrounding it, discussing the presence and potential roles of Aβ monomers, oligomers, protofibrils, and amyloid plaques in patients with Alzheimer's disease.
EP: 1.Apolipoprotein E4 in Alzheimer’s Disease
EP: 2.Importance of Early Diagnosis of Alzheimer’s Disease
EP: 3.Amyloid Precursor Protein and Amyloid Beta Species in Alzheimer’s Disease
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EP: 4.Amyloid Cascade Hypothesis of Alzheimer’s Disease
EP: 5.Contribution of Multiple Pathways to the Development of Alzheimer’s Disease
EP: 6.Utilization of Neuroimaging in Alzheimer’s Disease
EP: 7.CSF Testing and Blood-based Biomarkers in Alzheimer’s Disease
EP: 8.Utilization of APOE4 Genotype in Management of Alzheimer’s Disease
EP: 9.Alzheimer’s Disease Pipeline
EP: 10.The Future Outlook for Alzheimer’s Disease
- What is the amyloid cascade hypothesis of Alzheimer’s disease?
- When are Aβ monomers, oligomers, protofibrils and amyloid plaques seen in patients with Alzheimer’s disease?
- What are the strengths and weaknesses of amyloid cascade hypothesis?
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