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Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending May 16, 2025. 

NeurologyLive® Friday 5 — May 16, 2025

The FDA approved Fujirebio's Lumipulse G p-tau217/β-Amyloid 1-42 Plasma Ratio as the first in vivo blood test for early Alzheimer’s detection, demonstrating high diagnostic accuracy with strong correlations to amyloid PET and CSF test results.

FDA Clears Lumipulse Plasma Ratio as First Blood Test for Diagnosing Alzheimer Disease

Markted as Brekiya, Amneal Pharmaceuticals’ newly approved therapy offers a self-administered version of dihydroergotamine mesylate for adults with migraine or cluster headache.

FDA Approves First Autoinjector Form of DHE for Acute Migraine and Cluster Headache

Targeting tau pathology in preclinical Alzheimer disease could benefit from recruiting individuals positive for both Aß and GFAP biomarkers, improving patient selection and cost effectiveness.

Plasma GFAP May Enrich Patient Selection, Reduce PET Scans Required for Alzheimer Trials

Videos

The executive vice president of research at the National MS Society talked about the significance of the Dystel Prize, honoring researchers in MS whose scientific work has led to meaningful diagnostic or therapeutic advancements. [WATCH TIME: 2 minutes]

Recognizing Scientific Excellence and Impact in Multiple Sclerosis Research: Bruce Bebo, PhD

, has been with the team since September 2022. Follow her on Twitter 

The research portfolio director at the Muscular Dystrophy Association discussed the evolving ALS therapeutic landscape, highlighting advances in genetic and RNA-based interventions. [WATCH TIME: 6 minutes]

Advancing ALS Through Gene Therapies, Early Intervention, and Multidisciplinary Care: Brian Lin, PhD

Marco Meglio, Assistant Managing Editor for 

, has been with the team since October 2019. Follow him on Twitter 

Seif Elbualy, MD, discusses his role at the Brain and Spine Symposium and shares insights on the future of interventional pain management, evolving techniques, and pharmaceutical innovation.

Overviewing 2025 Baptist Health Brain and Spine Symposium: Exploring New Options in Chronic Pain Management

The director of the Tuberous Sclerosis Program at Cleveland Clinic provided clinical commentary on a novel clustering analysis in TSC, revealing how phenotype-genotype insights can lead to more personalized treatment and surveillance.

NeuroVoices: Ajay Gupta, MD, on Phenotyping Tuberous Sclerosis Complex Into Disease Clusters

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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Insomnia and Sleep Disorders in Primary Care Settings

Paul Doghramji, MD, FAAFP, provides insight on the use of current treatment modalities for insomnia and the management of sleep disorders in primary care clinics.

Paul Doghramji, MD, FAAFP, provides an overview of the prevalence of sleep disorders, including insomnia, in the primary care setting.

Prevalence of Sleep Disorders in Primary Care Clinics

Dr Paul Doghramji shares insight on reasons for the underdiagnosis of insomnia and the importance of treating sleep disorders concurrently with comorbidities.

Identification of Sleep Disorders in Primary Care Clinics

An expert in sleep medicine comments on approaching screening patients for insomnia or other sleep disorders in the primary care setting.

Screening for Sleep Disorders in Primary Care Clinics

Paul Doghramji, MD, FAAFP, discusses best practices for referring patients with sleep issues to a sleep specialist.

Patient Referrals for Sleep Disorder Management

Dr Paul Doghramji shares tips for communication with patients once an insomnia diagnosis has been made.

Approaching Patient Conversations for Sleep Disorder Management

An expert in sleep medicine provides insight on the use of traditional insomnia medications in patients as well as DORAs, and common challenges experienced with these treatment options.

Treatment Options for Insomnia

Paul Doghramji, MD, FAAFP, shares his personal experience with DORAs in clinical practice to manage insomnia and discusses treatment adherence with insomnia medications.

Using DORAs for the Treatment of Insomnia

Dr Paul Doghramji shares his approach to switching medications for the treatment of insomnia.

Treatment Adherence and Switching Treatments for Insomnia

An expert in sleep medicine highlights challenges in prescribing DORAs and importance of discussing insomnia with patients in the primary care setting.

Access and Treatment of Insomnia in Primary Care Clinics

Clinical

Lasso - DMD Peers and Perspectives NSP-21-NRD0157

 video series brings together pairs of expert clinicians and physicians to independently provide their insights on the latest and most up-to-date clinical care for specific neurologic diseases and disorders.

Identification of Sleep Disorders in Primary Care Clinics

EP: 1.Prevalence of Sleep Disorders in Primary Care Clinics

EP: 2.Identification of Sleep Disorders in Primary Care Clinics

EP: 3.Screening for Sleep Disorders in Primary Care Clinics

EP: 4.Patient Referrals for Sleep Disorder Management

EP: 5.Approaching Patient Conversations for Sleep Disorder Management

EP: 6.Treatment Options for Insomnia

EP: 7.Using DORAs for the Treatment of Insomnia

EP: 8.Treatment Adherence and Switching Treatments for Insomnia

EP: 9.Access and Treatment of Insomnia in Primary Care Clinics