Our May news includes memory replay disruption in Alzheimer disease, impulse control disorder in Parkinson disease, and return to play in TBI.
We present a selection of interesting neurology articles for the month of May in the following slides. See the slide legends for links to the article summaries.
Interesting Neurology: Alzheimer & Parkinson insights. May 2016
Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples. Abstract link. **** Interaction of tau with the RNA-binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Abstract link.
Patients with Rosacea Have Increased Risk of Dementia. Abstract link. ****Hyperhomocysteinemia Exacerbates Alzheimer’s Disease Pathology by Way of the Aβ-Fibrinogen Interaction. Abstract Link.
Eisai Announces FDA Approval of FYCOMPA® (perampanel) Oral Suspension for Adjunctive Therapy in the Treatment of Partial-Onset Seizures and Primary Generalized Tonic-Clonic Seizures. Press release. **** Prognostic Factors for Seizure Outcome in Patients with MRI-Negative Temporal Lobe Epilepsy: a Meta-Analysis and Systematic Review. Abstract link.
Migraine with Aura and Risk of Silent Brain Infarcts and White Matter Hyperintensities: an MRI Study. Abstract link. ****A Cohort Study Examining Headaches among Veterans of Iraq and Afghanistan Wars: Associations with Traumatic Brain Injury, PTSD, and Depression. Abstract link.
Rebound Syndrome in Patients with Multiple Sclerosis After Cessation of Fingolimod Treatment. Abstract Link. ****Exercising Impacts on Fatigue, Depression, and Paresthesia in Female Patients with Multiple Sclerosis. Abstract link.
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor. Abstract link. ****Clinical-Genetic Model Predicts Incident Impulse Control Disorders in Parkinson’s Disease. Abstract link.
Clinical Scales Do Not Reliably Identify Acute Ischemic Stroke Patients with Large-Artery Occlusion. Abstract link. ****Endovascular Treatment versus Medical Care Alone for Ischaemic Stroke: Systematic Review and Meta-Analysis. Abstract link.
Concussion Symptoms and Return to Play Time in Youth, High School, and College American Football Athletes. Abstract link. ****SleepâWake Disorders Persist 18 Months After Traumatic Brain Injury but Remain Underrecognized. Abstract link.