
NeurologyLive® Friday 5 — June 26, 2026
Key Takeaways
- Phase 2 Vibrance-2 findings support continued evaluation of alixorexton, an orexin-2 receptor agonist, as a potential mechanistic therapy for narcolepsy type 2.
- Peripheral neuropathy biomarker development is expanding beyond NfL to include muscle MRI signatures, immune-targeted markers, and microRNA platforms.
Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending June 26, 2026.
Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive's widespread coverage in neurology, ranging from newsworthy study findings and FDA action to expert interviews and peer-to-peer panel discussions.
Click the read more or watch now buttons for more details and information about each highlight.
1: Insights on Vibrance-2 Study Results of Alixorexton in Narcolepsy Type 2: Richard K. Bogan, MD, FCCP, FAASM
In a recent interview at SLEEP 2026,
2: Emerging Biomakers in Perpheral Neuropathy Beyond Neurofilament Light Chain: Brett Morrison, MD, PhD
In a recent interview at the 2026 PNS Annual Meeting,
3: Pride Month 2026: Understanding Seizure Risk and Gender-Affirming Hormone Therapy
In honor of Pride Month, held annually in June, neurologists Medha Reddy, MD, and Nicole Rosendale, MD, FAAN, discussed a new analysis suggesting that gender-affirming hormone therapy was not associated with an increased risk of seizure-related hospitalization among transgender women.
4: NeuroVoices: Michael Coleman, PhD, on Understanding Programmed Axon Death and Its Therapeutic Potential
In our latest NeuroVoices Q&A, Michael Coleman, PhD, professor of neuroscience at the University of Cambridge, discussed the biology of programmed axon death, the emergence of SARM1-targeted therapies, and the challenges of translating this pathway into treatments for neurologic conditions.
5: Using Serum Biomarkers to Monitor Multiple Sclerosis Disease Activity: Darin T. Okuda, MD, FAAN, FANA
In a recent interview,
Which conversation stood out most to you in this week’s NeurologyLive Friday Five?
Don’t have time to read or watch a full video interview?


















