The NeurologyLive® epilepsy clinical focus page provides information, podcasts, videos, and news about the latest FDA actions, clinical guideline updates, study and clinical trial findings, and interviews with physicians related to epilepsy and related epileptic conditions, including Lennox-Gastaut syndrome, Dravet syndrome, tuberous sclerosis complex, focal seizures, nonmotor seizures, and more.
August 26th 2025
Spanning across the United Kingdom, the United States, European Union, and Japan, the global phase 3 EMPEROR study of zorevunersen is expected to have data readout by the end of 2027.
Adding Experience to the National Health Institute Council: Amy Brin, MSN, MA, PCNS-BC
May 17th 2022The chief executive officer of the Child Neurology Foundation provided insight on her new position at the National Health Institute’s National Advisory Neurological Disorders and Stroke Council. [WATCH TIME: 4 minutes]
First Patient Treated in Adolescent Epilepsy Trial Assessing NeuroPace RNS System
May 12th 2022Since its approval for the treatment of medical refractory epilepsy in 2013, the closed-loop neuromodulation device has had its efficacy and safety confirmed in several pivotal studies and will now be assessed in focal epilepsy in the RESPONSE trial.
Significance, Impact of Social Support in Child Neurology: Amy Brin, MSN, MA, PCNS-BC
May 10th 2022The chief executive officer of the Child Neurology Foundation provided insight on the ongoing efforts to make children with neurological conditions feel inclusive in today’s society. [WATCH TIME: 3 minutes]
Steven Wolf, MD, on the State of Lennox-Gastaut Syndrome and the Improving the Diagnostic Process
May 8th 2022The director of the pediatric epilepsy program at Boston Children’s Health Physicians shared his expertise with the challenges associated with diagnosing LGS, how the REST-LGS tool may help, and the need to collect more data.
AAN Annual Meeting 2022: Top Expert Interviews
April 28th 2022Expert clinicians offer their insight on the associations between stroke and COVID-19, treatment for traumatic brain injury, the latest on aducanumab, priorities for research in migraine, and more, from the 2022 American Academy of Neurology Annual Meeting.
Treatment Optimization in Epilepsy and the Need to Individualize the Approach
April 24th 2022Jacqueline A. French, MD, discussed the factors that influence the challenges in treatment selection in epilepsy, and how patient conversations and comprehension of heterogeneity can help in the treatment selection process.
Significant Change in Valproate Prescribing Patterns Identified Following 2016 EMA Recommendations
April 23rd 2022The proportion of women exposed to valproate between the first and last trimester of pregnancy decreased alongside an increase in the proportion of women exposed to therapeutic alternatives such as lamotrigine and levetiracetam.
Risk Factors Identified in TBI for Early Posttraumatic Seizures, Posttraumatic Epilepsy
April 20th 2022Outcomes in TBI admission survivors at 24 months—including mortality, development of posttraumatic epilepsy, and use of antiseizure medications—were poorer for cases with early posttraumatic seizures after adjustment for confounders.
The New Bar Set for Therapies in Treatment-Resistant Epilepsy: Jacqueline A. French, MD
April 19th 2022The codirector of Epilepsy Clinical Trials at NYU Langone spoke to the progress that’s been made in treating refractory epilepsy and her hopes for the future of drug development in this area of medicine. [WATCH TIME: 5 minutes]