Videos

Experts featured in this series.

In this episode, moderator Dr. Mitzi Joi Williams discusses Anti-CD20 Therapies in multiple sclerosis with Dr. Stephen Krieger, Dr. Benjamin Greenberg, and Dr. Riley Bove. Dr. Williams notes that while three anti-CD20 agents are FDA-approved for MS (ocrelizumab approved in 2017, followed by ofatumumab and ublituximab), rituximab has been used off-label for many years. Though these agents target the same molecule, they differ in meaningful ways.

Experts featured in this series.

In "Why Anti-CD20 Therapy Has Become a Cornerstone of MS Treatment" episode, panelists explore the anti-CD20 drug class itself — a group of B-cell depleting therapies that have become the most commonly initiated treatments for MS in the United States. Experts recount that the field initially viewed B-cell targeting as counterintuitive in what was long considered a T-cell-mediated disease. However, experience and trial data have demonstrated that depleting CD19/CD20-positive B cells produces profound downstream immunological effects that dramatically suppress MS disease activity.

Experts featured in this series.

In “Unmet Needs and the Impact of Disease Modifying Therapies in Dravet Syndrome,” the panelists explore the limitations of current treatment approaches and discusses how emerging disease-modifying therapies may transform the future management of Dravet syndrome. Expert faculty review the significant advances achieved with currently available antiseizure medications while acknowledging that substantial unmet needs remain for many patients and families.

Experts featured in this series.

In this episode “Current Treatment Strategies for Dravet Syndrome,” the panelists explore how genetic findings influence treatment selection and long-term management in Dravet syndrome. Expert faculty discuss the practical realities of treating patients when clinical suspicion for Dravet syndrome exists before genetic confirmation is available, emphasizing the importance of initiating appropriate management early and avoiding therapies that may worsen outcomes.