Opinion|Videos|December 23, 2024

Evaluating Cognitive Health: Tools, Markers, and the Concept of Cognitive PIRA

Author(s)Gabriel Pardo, MD, FAAN
Martin Belkin, DO

Panelists discuss how clinicians can evaluate cognitive health using neuroimaging, cerebrospinal fluid (CSF)/blood biomarkers, and comprehensive assessments. Understanding concepts like cognitive progressive irreversible reductions in activity (PIRA) and focusing on multifaceted interventions—including lifestyle modifications, early detection, and personalized strategies—can help maintain cognitive wellness and mitigate decline.

Video content above is prompted by the following:

Which tools, imaging, CSF, or peripheral blood markers can clinicians use to evaluate cognitive health in a patient? Please explain.
What are your thoughts about the concept of cognitive PIRA?
What advice would you have for health care providers so they can help patients better maintain their cognitive health?

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