Karen J. Nolan, PhD: Functional Implementation of Robotics in Neurorehabilitation
October 1st 2019The senior research scientist in the Center for Mobility and Rehabilitation Engineering Research at Kessler Foundation spoke to the research being done into the functional implementation of exoskeletons in neurorehabilitation.
Gut Microbiota: The Key to Parkinson Disease?
October 1st 2019The professor of chemistry and chemical biology at Harvard University and Blavatnik National Laureate discussed the work she and colleagues have done on microbiome metabolism and what upcoming plans to pursue this further could achieve.
Lemborexant Proves Safe, Effective for Insomnia in Long-Term Phase 3 Study
September 30th 2019Year-long data presented at World Sleep 2019 suggest that Eisai’s lemborexant is safe and effective in treating adults with insomnia, supporting its recently submitted NDA. It is set to be reviewed by the FDA by late December.
CGRP: Paving the Path to Migraine and Its Treatment
September 30th 2019After a long period of time with minimally effective treatments for migraine, the growing understanding of the CGRP pathway has opened the door to a variety of new and highly efficacious therapies for patients with chronic and episodic forms of disease.
JZP-258 Shows Success In Stabilizing Cataplexy for Patients With Narcolepsy
September 28th 2019Data presented at World Sleep 2019 has suggested that the investigation Jazz Pharmaceuticals sodium oxybate agent, JZP-258, is efficacious and safe in treating patients with narcolepsy who have cataplexy.
AbobotulinumtoxinA Adds Upper Limb Spasticity to Pediatric Indication, Excluding Cerebral Palsy
September 27th 2019This regulatory approval in the treatment of pediatric patients aged 2 years and older with upper limb spasticity, excluding those with cerebral palsy, marks abobotulinumtoxinA (Dysport, Ipsen) as the first botulinum toxin approved for both upper and lower pediatric spasticity.
Karen J. Nolan, PhD: Translational Research Into Neurorehabilitation Exoskeletons
September 27th 2019The senior research scientist in the Center for Mobility and Rehabilitation Engineering Research at Kessler Foundation shared insight into the work she and her colleagues are doing to try to revolutionize the way exoskeletons can improve neurorehabilitation and gait challenges.
Zogenix Resubmits Fenfluramine NDA in Dravet Syndrome
September 26th 2019Following the receipt of a refusal to file letter from the FDA, Zogenix has resubmitted its application for fenfluramine hydrochloride (Fintepla), seeking approval for the treatment of seizures associated with Dravet syndrome.
Glenn Wylie, DPhil: The Future of Real-Time Neurofeedback
September 26th 2019The director of the Rocco Ortenzio Neuroimaging Center at Kessler Foundation spoke about the future of functional MRI in providing real-time neurofeedback, and how it might be incorporated as an end point in clinical trials.
Mitsubishi Tanabe Reveals Phase 3 Study for Continuous Carbidopa/Levodopa in Parkinson Disease
September 26th 2019The clinical development of ND0612 includes 2 doses; a low dose for mid-stage Parkinson patients experiencing loss of motor control on oral therapy, and a high dose for severe disease in which oral drugs are no longer effective.
Amantadine ER Capsules for Dyskinesia Show Consistent Safety, Improved Motor Skills
September 25th 2019Data of amantadine (Gocovri, Adamas) extended-release tablets suggested that the therapy is, in fact, safe and tolerable with a unique pharmacokinetic profile, and results in significant improvements in dyskinesia for patients with Parkinson disease.
Karen J. Nolan, PhD: Using Exoskeletons for Patients With Gait Challenges
September 25th 2019The senior research scientist in the Center for Mobility and Rehabilitation Engineering Research at Kessler Foundation spoke about using the exoskeleton and dermal skeleton devices in functional recovery for patients who have lost the ability to walk.
Glenn Wylie, DPhil: The Role of Functional MRI in Research
September 24th 2019The director of the Rocco Ortenzio Neuroimaging Center at Kessler Foundation shared insight on the abilities functional MRI have provided researchers and how it has made an impact on the testing of interventions for a number of neurologic conditions.
Danielle Andrade, MD, MSc: Communicating and Network Building in Epilepsy Care
September 24th 2019The professor of medicine, neurology, at the University of Toronto shared insight into the importance of communication and a good network of physicians to an adult neurologist caring for patients with epilepsy.
EMA Committee Advises Removing MS Pregnancy Contraindications for Peginterferon and Interferon Beta
September 23rd 2019Based on datasets from 2 national registries and the European Interferon Beta Pregnancy Registry, the EMA’s Committee for Medicinal Products for Human Use has given a positive opinion to remove the contraindications, which would allow the Biogen agents to be used by pregnant and breastfeeding women with multiple sclerosis.
World Alzheimer Day 2019: Key Takeaways From Leaders in Alzheimer Disease and Dementia
In recognition of World Alzheimer Day, experts in Alzheimer disease and dementia share insight from the latest Alzheimer Disease International's yearly World Alzheimer Report.