The NeurologyLive® headache and migraine clinical focus page offers information, podcasts, videos, and news and interviews with physicians related to the care of patients with headache disorders such as chronic and episodic migraine, cluster headache, tension-type headache, and more. The page includes updates on the latest FDA actions, clinical guidelines, and study and clinical trial findings.
August 29th 2025
Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 29, 2025.
Investigational Migraine Preventive ALD1910 Doses First Phase 1 Patient
October 14th 2019Alder Biopharmaceuticals announced the dosing of the first patient with ALD1910, its investigational monoclonal antibody that inhibits PACAP to prevent migraine. The study is aiming to enroll 100 individuals with results in mid-to-late 2020.
Lasmiditan Approved for Acute Migraine Treatment in Adults
October 11th 2019Eli Lilly’s lasmiditan (Reyvow) tablets are the first member of the ditan class approved for use in adults with migraine with or without aura, offering patients who have an inadequate response to other therapies a new acute treatment option.
Upsher-Smith Launches Sumatriptan Nasal Spray for Acute Migraine Treatment
October 2nd 2019Originally approved by the FDA in January, sumatriptan nasal spray was acquired by Upsher-Smith in a territory rights agreement with Dr. Reddy’s Laboratories in June, as well as its 3-mg injection formulation (Zembrace SymTouch).
CGRP: Paving the Path to Migraine and Its Treatment
September 30th 2019After a long period of time with minimally effective treatments for migraine, the growing understanding of the CGRP pathway has opened the door to a variety of new and highly efficacious therapies for patients with chronic and episodic forms of disease.
Paul Durham, PhD: A Combination Approach With nVNS in Migraine
September 6th 2019The distinguished professor and director of cell biology at Missouri State University discussed the use of nVNS in migraine treatment and whether or not it can replace the use of or be used in conjunction with triptans—a medication on which many patients fail or report poor response on.
Trends in Migraine Care Reveal Treatment Gaps and Education Barriers
August 19th 2019The director of the MedStar Georgetown Headache Center and associate professor of neurology at MedStar Georgetown University Hospital discussed the ongoing efforts in drug development and what the ideal future may hold for migraine medicine.
The Symbiotic Relationship of Artificial Intelligence and Neurology
August 18th 2019The associate chief of the MS division and professor of neurology at the University of Pennsylvania described the relationship between artificial intelligence and medicine, and how he sees it evolving in the future.
AAN and AHS Release Pediatric Migraine Guidelines
August 15th 2019The American Academy of Neurology and American Headache Society have released 2 sets of guidelines regarding the acute and preventive treatment of migraine in children and teenagers, with a focus on shared decision-making, patient education, and needs for future research.