The NeurologyLive® Narcolepsy Disease Spotlight page offers specific updates and coverage on the latest expert conversations and data readouts related to the treatment and management of patients with the sleep disorder.
July 21st 2025
New study reveals alixorexton significantly improves wakefulness and reduces daytime sleepiness in narcolepsy type 1, paving the way for phase 3 trials.
Low-Sodium Oxybate Improves Daytime Sleepiness and Sleep Architecture in Phase 4 Narcolepsy Trial
June 11th 2025Findings from the Jazz DUET study presented at SLEEP 2025 showed that low-sodium oxybate reduced daytime sleepiness and improved sleep parameters in patients with narcolepsy types 1 and 2.
Real-World Data Show Similar Comorbidity Rates With and Without Sodium Oxybate Treatment
April 21st 2025Data suggest no significant differences in comorbidity rates in a newly published study, highlighting dosing challenges and treatment patterns in patients receiving immediate-release sodium oxybate.
World Sleep Day with Dr. Eric Olson: Advancing Sleep Health and Awareness
March 14th 2025On World Sleep Day, the president of the American Academy of Sleep Medicine discussed the importance of sleep for health, the risks of sleep deprivation, nonpharmacologic strategies to improve sleep, and the need for greater awareness of sleep disorders.
FAERS Data Analysis Reveals Insights on Safety Profiles of Narcolepsy Treatments
February 23rd 2025A recent analysis identified potential safety concerns associated with pitolisant, sodium oxybate, solriamfetol, and modafinil, highlighting distinct adverse event profiles for each narcolepsy treatment.
Hypertension Risk Elevated in Normotensive Patients With Narcolepsy Starting Sodium Oxybate
February 22nd 2025Normotensive patients with narcolepsy on sodium oxybate had over 50% of a higher risk of new-onset hypertension or antihypertensive medication use compared with nonusers of the treatment.
Patient Perspective on the Role of Social Support in Managing Narcolepsy: Julie Flygare, JD
February 5th 2025The president and CEO at Project Sleep talked about the foundational role of social connections and peer support in improving quality of life for individuals with narcolepsy. [WATCH TIME: 5 minutes]
Cognitive Behavioral Therapy-Insomnia Demonstrates Effectiveness in Improving Cancer-Related Fatigue
January 31st 2025Cognitive behavioral therapy for insomnia, a multicomponent psychotherapy, consists of sleep restriction, stimulus control, cognitive restructuring, relaxation training, and sleep hygiene.
Meta-Analysis Confirms Efficacy of Sodium Oxybate in Managing Narcolepsy Symptoms
January 26th 2025Recent findings from an analysis showed that sodium oxybate significantly reduced narcolepsy symptoms, including cataplexy and excessive daytime sleepiness, among patients with the sleep disorder.
Curving Complications Associated With Narcolepsy: Mihaela Nowak, MD
January 17th 2025The neurologist and sleep disorder specialist at Allegheny Health Network discussed the challenges with preventing narcolepsy and the strategies patients can take to improve their overall prognosis. [WATCH TIME: 4 minutes]
Advancing Future Drug Development for Narcolepsy: Mihaela Nowak, MD
January 6th 2025The neurologist and sleep disorder specialist at Allegheny Health Network provided an in-depth exploration of the current advancements and future directions in narcolepsy drug development. [WATCH TIME: 3 minutes]