Latest Conference Coverage

Tanuja Chitnis, MD: Consequences of Incomplete Recovery in MS

The director of the Partners Pediatric MS Center at Massachusetts General Hospital for Children provided insight on the consequences of incomplete relapse recovery in multiple sclerosis.

Carrie Hersh, DO, MSc: Addressing Progressive Disease in MS

The assistant professor of neurology at the Lerner College of Medicine and neurologist at Luo Ruvo Center for Brain Health, both of Cleveland Clinic, spoke to the importance of preventing progression in MS and treating the non-inflammatory aspects of the disease.

Augusto Miravalle, MD: How Cladribine Sets Itself Apart in MS

The associate professor in the department of neurology at the University of Colorado and neurologist at Advanced Neurology of Colorado discussed the advantages of cladribine and details of the ongoing CLICK-MS study.

Cladribine Effectively Reduces Risk of Secondary Progressive Multiple Sclerosis

Similar effects were observed for each proxy SMPS component when compared with placebo.

Endovascular Therapy Displays Similar Outcomes to Intravenous Thrombolysis

When performed by itself, endovascular therapy had greater rates of intracranial hemorrhage compared to a combination of both endovascular therapy and intravenous thrombolysis.

CNM-Au8 Improves Visual Acuity in Patients With MS With Optic Neuropathy

This included the first 34 participants from the VISIONARY-MS study, which is currently ongoing with the orally delivered suspension of clean-surfaced, faceted gold nanocrystals.

Cladribine Shows Durable Efficacy in Relapsing Multiple Sclerosis

Data from the CLARITY extension trial suggest that the durability of treatment with cladribine extended beyond 24 months in those with relapsing-remitting multiple sclerosis.

Incomplete Recovery From MS Relapse May Contribute to Long-Term Disability

Recovery status may be a useful tool to predict long-term outcomes in patients with relapsing forms of multiple sclerosis.

Ofatumumab Nearly Clears B-Cell Activity With At-Home Dosing

The investigational MS therapy is currently under review with the FDA, with a PDUFA date set for June 2020.

Earlier Ocrelizumab Treatment in MS Has Positive Long-term Impact

Compared with patients who initially received interferon treatment, those given ocrelizumab had superior disability progression after a 6-year follow-up.

Siponimod Significantly Slows MS Disability Progression in Patients With Shorter Disease Duration

Patients with a disease duration of <16 years demonstrated a significantly greater reduction in risk for confirmed disability progression (CDP) at 3 and 6 months.

Early Administration of Tranexamic Acid May Reduce Intracerebral Hemorrhage in Stroke

Phase 2 STOP-AUST data suggest that the antifibrinolytic agent may be able to reduce ICH in spot sign positive patients with stroke when administered within 2 to 3 hours of onset, warranting further study.

Low-Dose Tenecteplase Ideal for Stroke Treatment

New study data from ISC 2020 suggest that patients with stroke can be effectively treated with tenecteplase at a lower dose of 0.25 mg/kg, reducing the need for mechanical clot removal.

Functional Outcomes Improved by Mobile Stroke Units

Stroke patients experienced higher rates of thrombolysis as well as faster alarm to treatment times when mobile stroke units were present.

Lower LDL-C Target May Help Prevent Vascular Events Following Ischemic Stroke

The composite primary end point of the study occurred in 9.6% of patients in the lower-target LDL-C group compared with 12.9% in the higher target group.

Novel Stroke Treatment Nerinetide Falls Short in Phase 3

Despite missing the primary end point, data from a subset of patients suggest that the novel peptide may be beneficial in those who have not received alteplase.

Portable MRI Safe and Functional for Bedside Stroke Imaging

Despite the conventional need for patients to travel to MRI devices, the use of a point-of-care, portable scanner has proven to be a feasible method of acquiring clinically useful images.

Poststroke Seizures Associated With Increased Risk for Functional Disability, Death

Patients 65 and under were more likely to develop seizures following a stroke than older patients.

Shingles Vaccine Linked to Lower Risk of Stroke

The beneficial impact on stroke risk appeared to be greater in patients age 79 and younger than in the older patients examined.

Risk Score May Help Identify Migraine Patients At Risk for Stroke

The model may help clinicians enact preventative measures for those with migraine with aura at an early stage.

Lara Jehi, MD: Weighing Cognitive Risks in Epilepsy Surgery

The professor of neurology and epilepsy specialist at the Cleveland Clinic Lerner College of Medicine discussed the difficult treatment decisions faced when undergoing epilepsy surgery.

Zachary Grinspan, MD, MS: Collaborating Across Specialties to Improve Outcomes

The director of the Pediatric Epilepsy Program and an MD candidate at Weill Cornell Medicine detail the steps needed to take to improve outcomes in status epilepticus.

The Evolution of Epilepsy Care: Where We Are Going

Page B. Pennell, MD, president of the American Epilepsy Society, shared her thoughts on the epilepsy treatment landscape, managing women with epilepsy, and the need for multidisciplinary involvement and communication.

Page B. Pennell, MD: Improving Epilepsy Care in 2020 and Beyond

The president of the American Epilepsy Society and director of epilepsy research at Brigham and Women’s Hospital outlined the state of epilepsy care and what we can expect in 2020.

Zachary Grinspan, MD, MS: Improving Adherence to Status Epilepticus Protocols

The director of the Pediatric Epilepsy Program is joined by an MD candidate from Weill Cornell Medicine to discuss the protocol used to treat patients with status epilepticus.

Erin Conrad, MD: Identifying the Seizure Onset Zone

The epilepsy fellow at the hospital of the University of Pennsylvania detailed why locating the seizure onset zone plays a crucial role in successful epilepsy surgery.

Elizabeth Gerard, MD: Explaining the Breastfeeding Gap In Epilepsy

The associate professor of neurology and director of the Women With Epilepsy Program at Northwestern University Feinberg School of Medicine detailed the ongoing questions about assessing the gaps in breastfeeding between women with, and without, epilepsy.

Elizabeth Gerard, MD: Successful Breastfeeding in Women With Epilepsy

The associate professor of neurology and director of the Women With Epilepsy Program at Northwestern University Feinberg School of Medicine spoke about the findings of the MONEAD study and their implications for women with epilepsy.

The Potential of Gene Therapy to Treat SCN1A-Positive Epilepsy

The medical director of the Comprehensive Epilepsy Clinic at Nicklaus Children’s Hospital shared his insight into the potential of using an SCN1A-targeted adeno-associated viral vector-based gene therapy in epilepsy.

Elizabeth Gerard, MD: Advising Women With Epilepsy to Breastfeed

The associate professor of neurology and director of the Women With Epilepsy Program at Northwestern University Feinberg School of Medicine spoke about the need for consistency in the messaging conveyed to women with epilepsy who are having children.