Stroke

In a multiday ascending dose trial, pharmacokinetic analysis indicated a direct linear relationship between drug dosing concentration and blood plasma levels for each of the 5 days of dosing.

After adjusting for stroke severity, prestroke physical activity still accounted for a 52% lowered risk for long-term morality following intracerebral hemorrhage and 48% after ischemic stroke.

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Patients who received tirofiban did not differ from placebo in terms of 90-day outcomes, and they showed an increased incidence of symptomatic intracranial hemorrhage.

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Neurology News Network for the week ending August 20, 2022. [WATCH TIME: 4 minutes]

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 19, 2022.

Mendelian randomization analyses identified a significant association between genetically determined chronic kidney disease and intracerebral hemorrhage risk, supporting a causal association between the 2 conditions.

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Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 12, 2022.

When combing all 26 studies irrespective of methods, the lowest age-specific divergence in incidence was seen in 3 Southern European studies, and the most pronounced divergence in North American studies.

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Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 5, 2022.

The Alnylam Pharmaceuticals agent, already approved for the treatment of polyneuropathy in those with hATTR amyloidosis, has now shown promise as a therapeutic option for patients with ATTR amyloidosis with cardiomyopathy.

Catch up on any of the neurology news headlines you may have missed over the course of the last month, compiled all into one place by the NeurologyLive® team.

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Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending July 29, 2022.

In addition to reduced times to treatment, implementation of field stroke triage led to significantly lower rates of disability for both the entire cohort and those independent at baseline among those with large vessel occlusions.

Data from a cohort of more than 111,000 women showed that presence of endometriosis increased stroke risk by 34%.

Those with an optimal Life's Simple 7 score had roughly a 30% to 43% lower lifetime stroke risk than those with an inadequate Life's Simple 7 categorization, corresponding to almost 6 additional years of stroke-free life.

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Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is headache and migraine.