Long-Term DMT Exposure Prevents Disability in Multiple Sclerosis
An analysis of MSBase data including more than 14,000 patients with MS suggests that disease-modifying therapies are effective in improving disability outcomes in relapsing disease.
Nilotinib Shows No Beneficial Effect in Patients with Parkinson
Researchers from Northwestern University found nilotinib had an acceptable safety profile, but lacked efficacy that would encourage further study in patients with Parkinson disease.
Brian Wainger, MD, PhD: Motor Neuron Excitability in ALS
The assistant professor of neurology and anesthesiology at Harvard Medical School provided context on the potential of motor neuron excitability in patients with ALS.
Multiple Sclerosis Fatigue
Topiramate Oral Solution NDA Filing Accepted for 3 Indications
The agent will aim to be the first and only FDA-approved liquid formulation of topiramate, with a PDUFA date set in Q3 of 2021.
Merit Cudkowicz, MD, MSc: Assessing NurOwn in ALS
The director of the Healey & AMG Center for ALS spoke to the recent topline results of a phase 3 study of NurOwn in patients with the neuromuscular disease.
This Week on NeurologyLive — January 4, 2021
Here's what is coming soon to NeurologyLive.
Pavel Klein, MD: Brivaracetam Efficacy Inversely Proportional to Number of Lifetime AEDs
The director of the Mid-Atlantic Epilepsy and Sleep Center urged physicians to try and find the right medications for their patients as early as possible.
Athira Pharma Awarded $15 Million Grant to Investigate ATH-1017 for Alzheimer
Both ongoing ACT-AD and LIFT-AD studies are assessing Athira’s investigational therapy ATH-1017.
SOD1 Variants Show Significant Association with ALS Risk
Researchers from the University of Turin also found that an NEFH variant showed a protective association with ALS.
NeurologyLive Friday 5 — January 1, 2021
Take 5 minutes to catch up on NeurologyLive's highlights from the week ending January 1, 2021.
QoL Issues in the Management of Multiple Sclerosis
William Rosenfeld, MD: Finding Ideal Combinations of Cenobamate and Concurrent ASMs
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team succeeded at titrating cenobamate early in the study.
Episode 26: Digital Approaches to Comprehensive Care in MS
"Mind Moments," a podcast from NeurologyLive, brings you an exclusive interview with Leigh Charvet, PhD.
NeurologyLive Year in Review: Top Podcast Episodes of 2020
Catch up on the best and most listened to episodes of the NeurologyLive Mind Moments podcast, featuring exclusive interviews with experts in neurology.
The Global Push for Mechanical Thrombectomy in Stroke Care
Increasing the use and accessibility of mechanical thrombectomy may reduce the burden of stroke on a global scale.
Challenges in Optimally Treating Multiple Sclerosis
Pavel Klein, MD: Efficacy of Brivaracetam on Refractory Epilepsy
The director of the Mid-Atlantic Epilepsy and Sleep Center urged physicians to actively look for new medications for patients to try.
Episode 25: 2020 Wrap Up: Silver Linings
"Mind Moments," a podcast from NeurologyLive, brings you an exclusive interview with Jennifer Frontera, MD, and a number of others.
NeurologyLive Year in Review: Top Video Interviews of 2020
Look back on some of our most popular video interviews with experts in the field, including discussions on stroke, migraine, Parkinson disease, dementia, and more.
RGMa Inhibition for Repair and Protection in Multiple Sclerosis
Patients with MS have an urgent need for therapies that can reverse neurologic disability by promoting remyelination, and RGMa inhibition may help meet that need.
Jude Savarraj, PhD: Applying Machine Learning to Healthcare
The research scientist from the University of Texas Medical School discussed some of the challenges and opportunities that machine learning presents in patient care.
NeuroVoices: Jennifer Robblee, MD, on Learning from Migraine Care in 2020
Jennifer Robblee, MD, neurologist, Barrow Neurological Institute, shares her takeaways about how migraine care shifted this year and how it may continue to shift going forward.
NeurologyLive Year in Review: Top FDA Approvals of 2020
The approvals introduced several new agents into a number of patient populations, including much-needed additions to some diseases lacking a large number of options.
Data Evolution in Alzheimer Disease: Is the Future Digital?
Digital biomarkers offer promise to revolutionize the diagnosis and treatment of Alzheimer disease via our increasing ability to gather active and passive data.
William Rosenfeld, MD: Balancing Cenobamate and Concomitant ASMs
The neurologist from the Comprehensive Epilepsy Care Center for Children and Adults, in St. Louis, Missouri, discussed how his team studied the interactions of ASMs and cenobamate.
Updates in Approaches to Acute Migraine Care
In a NeurologyLive® Peer Exchange, a panel of migraine specialists discussed the novel therapies in development and those entering the market for the treatment of acute migraine.
NeurologyLive Year in Review: Top Video Series of 2020
Catch up on some of our most popular Peer Exchange panels with experts in the field, including discussions on epilepsy, migraine, multiple sclerosis, and more.
Cerebrospinal Fluid in Diagnosing Multiple Sclerosis
Recent Advances in the Understanding of Insomnia
Guest Editor-in-Chief Karl Doghramji, MD, FAASM, DFAPA, discusses the recent steps forward that have been made in the care of patients with insomnia.