Autologous Hematopoietic Stem Cell Transplantation Safe in Aggressive MS
Researchers observed statistically significant improvements of the EDSS score along with a majority of patients showing no new enlarging or gadolinium-enhancing MRI lesions.
Previously Unrecognized Dystonia is a Prevalent Clinical Feature of Angelman Syndrome
Researchers found that 93% of patients with AS exhibited dystonia in their limbs, mouth, neck, or trunk.
The Potential of Avalglucosidase Alfa in Late-Onset Pompe Disease Treatment
With promising data presented at WORLDSymposium 2021 and a PDUFA date looming in May, investigator Priya S. Kishnani, MD, offered her insight on Sanofi’s investigational therapy.
Expanding Research of Sleep and Cognitive Risks Associated: Christian Agudelo, MD
The Evelyn F. McKnight Neurocognitive Scholar at the University of Miami Miller School of Medicine discussed observing how sleep may impact cognitive decline in different populations.
Prevalence, Temporal Patterns Identified in Seizures in Focal Epilepsy
Using the largest existing cEEG data set, researchers identified seizure chronotypes at multiple timescales, noting that circadian and multidien seizure cycles are equally strong and highly prevalent.
Using Midazolam Nasal Spray for Seizure Clusters
This Week on NeurologyLive — February 15, 2021
Here's what is coming soon to NeurologyLive.
Survey Clarifies Key Psychosocial Issues, Symptoms for Young Patients With Narcolepsy
The data revealed some of the more common and problematic symptoms, challenges, and comorbidities that persist for these individuals despite care.
Reassessing CP Diagnosis to Involve Child Neurologists: Bhooma Aravamuthan, MD, DPhil
The assistant professor of pediatric neurology at Washington University in St. Louis spoke to the results of a recent survey she and colleagues conducted.
New Clinical Study Evaluating Parkinson PET Imaging Tracer Initiated
ACI-12589 aims to become the world’s first diagnostic tool for assessing brain alpha-synuclein pathology in patients with Parkinson disease.
Adapting Speech, Occupational, Mental Health Therapy to Telehealth: James Beck, PhD
The chief scientific officer of the Parkinson’s Foundation discussed the state of mental health services for people with Parkinson disease during the COVID-19 pandemic.
Avalglucosidase Alfa Shows Success in Late-Onset Pompe Disease
Data presented at WORLDSymposium 2021 suggest that the Sanofi enzyme replacement therapy is effective and safe compared to the company’s other agent, alglucosidase alfa.
Cognitive Behavioral Therapy vs. Pharmacological Treatments for Insomnia: Jennifer Martin, PhD
The AASM board of directors' member and professor of medicine at UCLA discussed the benefits of CBT-I and its efficacy compared to pharmacological treatments.
uniQure Receives Positive Recommendation from DSMB for Huntington Disease
AMT-130 is uniQure’s first clinical program focusing on the central nervous system incorporating its proprietary miQURE silencing technology platform.
FDA Approves Genio OSA Therapy, Improved Motor Function With FUS, Soticlestat Evaluated in Dravet Sydrome
Neurology News Network for the week ending February 13, 2021.
Brain Neurotherapy Bio Brings Clinical Programs for Parkinson and MSA to AskBio
Both therapeutic programs utilize AAD2-GDNF gene therapy targeted to brain structures vulnerable to Parkinson disease and multiple system atrophy.
The Role of Child Neurologists in Diagnosing Cerebral Palsy: Bhooma Aravamuthan, MD, DPhil
The assistant professor of pediatric neurology at the Washington University in St. Louis spoke to the roles of multiple specialists in CP diagnosis.
NeurologyLive Friday 5 — February 12, 2021
Take 5 minutes to catch up on NeurologyLive's highlights from the week ending February 12, 2021.
Improving Poststroke Mobility With Brain Implants: Mijail Serruya, MD, PhD
The assistant professor of neurology at Thomas Jefferson University discussed the details using a brain implant and robotic brace in a newly initiated clinical trial.
West and West-like Syndrome Most Common Severe Epilepsy Syndromes at Infancy
Researchers found that infantile epileptic encephalopathy and SEI with migrating focal seizures had the highest mortality rates at 2 years of age.
Assessing High-Intensity Exercise to Prevent Alzheimer Disease: Stephen Rao, PhD; Jay Alberts, PhD
A duo of researchers from Cleveland Clinic outlined their new 5-year study that tests home-based intervention in high-risk individuals for Alzheimer disease.
Episode 29: Developing A Seizure Action Plan
"Mind Moments," a podcast from NeurologyLive, brings you an exclusive conversation with Scott Perry, MD; Orrin Devinsky, MD; and Tracy Salazar, PhD.
Older Adults With Epilepsy Experience Faster Cognitive Decline
Mini-mental state exam scores declined significantly faster in adults with prevalent and incident epilepsy, while digit symbol substitution test scores declined significantly faster in prevalent epilepsy.
2020 American Epilepsy Society Post-Conference Perspectives
The director of the Dartmouth Epilepsy Program and chairwoman of AES 2020 discussed some of the major topics from the previously completed annual meeting and where epilepsy research is trending.
Idiopathic Intracranial Hypertension More Likely With High BMI, Socioeconomic Deprivation
Socioeconomic deprivation was associated with IIH independently of BMI in women but not men.
Differentiating Seizure Action Plans by Epilepsy Type
A roundtable discussion featuring Scott Perry, MD, Orrin Devinsky, MD, and Tracy Salazar, PhD, details the way seizure action plans can differ depending on seizure phenotype and frequency of seizures.
Rapid Tapering Method With Prednisone Demonstrates Efficacy, Safety in Myasthenia Gravis
The proportion of patients treated with prednisone and the prednisone dose tended to be lower in the rapid-tapering group at 15 months compared to slow-tapering arm.
Clinically Meaningful Migraine Prevention: Richard B. Lipton, MD
The director of the Montefiore Headache Center discussed how rimegepant was observed to produce clinically meaningful improvements in migraine prevention.
NeurologyLive Wants Your Feedback: Q1 2021 Audience Survey
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FDA Approves MRI Labeling for Genio Obstructive Sleep Apnea Therapy
The Genio system offers bilateral stimulation of the hypoglossal nerve branches, which may lead to potentially greater airway opening for patients with obstructive sleep apnea.
