
Opinion|Videos|November 2, 2026
Clinical Takeaways & Management Implications
Author(s)Suraj Muley, MD, FAAN, FRCP, FACP
Dr. Muley synthesizes the data: durable response at 52 weeks in both AChR+ and MuSK+ patients with no new safety signals.
Advertisement
Episodes in this series

Dr. Muley synthesizes the data: durable response at 52 weeks in both AChR+ and MuSK+ patients with no new safety signals. He calls for differentiating inebilizumab from downstream therapies (complement inhibitors, FcRn blockers), which do not address upstream B cell mechanisms and may yield less durable responses. For clinicians seeking a treatment that targets autoantibody production at its source with sustained benefit, inebilizumab represents a meaningful option.
Advertisement
Related to this article

The FDA accepted uniQure's biologics license application for ifezuntirgene inilparvovec and granted it Priority Review, setting a target action date of May 1, 2027.

Jeffrey Cohen, MD, professor of neurology and staff physician at the Cleveland Clinic Mellen Center for Multiple Sclerosis, discusses interim BREAKFREE-2 findings for zola-cel, a CD19-directed CAR T cell therapy, in relapsing and progressive MS.

Interim phase 1b/2a data showed all patients treated with high- or low-dose BB-301 for oculopharyngeal muscular dystrophy met formal response criteria.

Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is the history of neurology!

Although ocular signs in LEMS are typically mild and appear late, recognizing them alongside proximal weakness and autonomic symptoms can speed diagnosis and earlier detection of an associated lung cancer.
Advertisement
Advertisement
Trending on NeurologyLive - Clinical Neurology News and Neurology Expert Insights
1
Examining Trontinemab in Early Alzheimer Disease: The Phase 3 TRONTIER 1 and 2 Trials
2
Understanding Cemdisiran's Mechanism of Action in Myasthenia Gravis
3
Benitec Reports Positive Interim Results for BB-301 in Oculopharyngeal Muscular Dsytrophy
4
Insights on the Updated 2026 AHA/ASA Stroke Rehabilitation Guidelines
5



