
Opinion|Videos|November 2, 2026
MINT OLP 1-Year: MG-ADL & QMG Durability
Author(s)Suraj Muley, MD, FAAN, FRCP, FACP
Dr. Muley reviews the MINT open-label period 1-year interim data.
Advertisement
Episodes in this series

Dr. Muley reviews the MINT open-label period 1-year interim data. Of 238 enrolled participants, 208 entered the 3-year OLP and 188 completed the 1-year mark. MG-ADL improvement from RCP baseline: 6.1 points (inebilizumab/inebilizumab) and 5.9 points (placebo/inebilizumab). Mean QMG improvement: 7.3 and 6.9 points, respectively. He emphasizes that these results confirm durable response through 12 months and notes no new safety signals emerged during sustained B cell depletion.
Advertisement
Related to this article

The FDA accepted uniQure's biologics license application for ifezuntirgene inilparvovec and granted it Priority Review, setting a target action date of May 1, 2027.

Jeffrey Cohen, MD, professor of neurology and staff physician at the Cleveland Clinic Mellen Center for Multiple Sclerosis, discusses interim BREAKFREE-2 findings for zola-cel, a CD19-directed CAR T cell therapy, in relapsing and progressive MS.

Interim phase 1b/2a data showed all patients treated with high- or low-dose BB-301 for oculopharyngeal muscular dystrophy met formal response criteria.

Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is the history of neurology!

Although ocular signs in LEMS are typically mild and appear late, recognizing them alongside proximal weakness and autonomic symptoms can speed diagnosis and earlier detection of an associated lung cancer.
Advertisement
Advertisement
Trending on NeurologyLive - Clinical Neurology News and Neurology Expert Insights
1
Examining Trontinemab in Early Alzheimer Disease: The Phase 3 TRONTIER 1 and 2 Trials
2
Understanding Cemdisiran's Mechanism of Action in Myasthenia Gravis
3
Benitec Reports Positive Interim Results for BB-301 in Oculopharyngeal Muscular Dsytrophy
4
Insights on the Updated 2026 AHA/ASA Stroke Rehabilitation Guidelines
5



