
Opinion|Videos|November 2, 2026
MuSK+ Subgroup -- RCP and OLP Results
Author(s)Suraj Muley, MD, FAAN, FRCP, FACP
Dr. Muley covers the MuSK-positive subgroup: 48 patients randomized, 46 entered the OLP, 44 completed 26 weeks.
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Dr. Muley covers the MuSK-positive subgroup: 48 patients randomized, 46 entered the OLP, 44 completed 26 weeks. RCP results: MG-ADL reduction 4.1 (inebilizumab) vs. 3.1 (placebo); QMG reduction 5.0 vs. 4.2. At 52 weeks (26 weeks into OLP): MG-ADL 5.6 (ineb/ineb) and 5.1 (pbo/ineb); QMG 6.1 and 7.4. He notes this is a descriptive, non-statistical analysis but highlights the clinical significance of benefit in a distinct, often more severe subpopulation.
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