
Neurology News Network for the week ending May 2nd, 2026. [WATCH TIME: 5 minutes]

Neurology News Network for the week ending May 2nd, 2026. [WATCH TIME: 5 minutes]

In this episode, "Navigating CIDP Guidelines, Misdiagnosis, and Disease Variants," the panelists in neurology and neuromuscular medicine explore the practical utility of the 2021 EAN/PNS CIDP guidelines and the considerable complexity introduced by disease variants. The discussion opens with a question about monophasic CIDP, with one expert noting that 20–30% of patients can achieve drug-free remission after initial treatment, suggesting a subset of patients experience a self-limiting course that nonetheless meets the diagnostic threshold of progression or relapse beyond two months.

Richard Nowak, MD, MS, outlines the biologic rationale for CD19-targeted therapy in generalized myasthenia gravis, highlighting how inebilizumab differs from CD20-directed approaches and why broader B-cell depletion may offer clinical advantages.

The clinical professor of adult neurology at Stanford University discussed data he presented at AAN's 2026 Meeting [WATCH TIME: 4 minutes]

Welcome back to another NeurologyLive Peer Exchange series. The panel opens with a discussion of CIDP prevalence, noting that estimates vary depending on the diagnostic criteria used. A strict case definition from a New South Wales population study places prevalence at approximately 1 per 100,000, while a more clinically based study from Olmsted County suggests a higher figure of around 1 in 10,000. One expert contextualizes this further, estimating that roughly 40,000–50,000 patients in the U.S. are affected, and that CIDP accounts for approximately 20% of patients presenting to peripheral neuropathy centers with initially unrecognized neuropathy. The panel characterizes CIDP as rare but not ultra-rare.

Katherine B. Peters, MD, PhD, breaks down how IDH mutations drive 2-hydroxyglutarate production and how this process contributes to both tumor growth and seizure activity in glioma.

Katherine B. Peters, MD, PhD, outlines how seizures shape the lived experience of patients with grade 2 IDH-mutant glioma, highlighting their impact on independence, employment, and long-term quality of life.

The associate professor of neurology at the Perelman School of Medicine at the University of Pennsylvania discussed pivotal data on zilganersen, highlighting its efficacy, safety, and potential as the first disease-modifying therapy for Alexander disease.

Duchenne trials accelerate with next-gen gene therapy, muscle-protecting drugs, and improved exon-skipping approaches—aiming for safer, longer-lasting benefits and easier dosing.

Clinicians tailor Duchenne treatment over time, balancing steroid benefits, side effects, ambulation changes, and required monitoring for newer therapies and families.

The founder and president of the Indian Federation of Neurorehabilitation highlighted emerging technologies and evolving therapeutic strategies shaping the future of neurorehabilitation. [WATCH TIME: 5 minutes]

The deputy director at Association of Movement Disorder Advanced Practice Providers (AMDAPP) recapped key themes in movement disorders presented at the 2026 AMDAPP conference. [WATCH TIME: 5 minutes]

The assistant professor in the Department of Chemistry and Biochemistry at University of Nevada, Las Vegas reflected on receiving the first MDA Research Momentum Award at the 2026 MDA Conference. [WATCH TIME: 2 minutes]

The director of the autoimmune neurology program at the University of Colorado discussed data she presented at AAN's 2026 Meeting [WATCH TIME: 5 minutes]

Neurology News Network for the week ending April 25th, 2026. [WATCH TIME: 5 minutes]

Mitzi Joi Williams, MD, and Carol Coleman break down insurance basics, prior authorizations, and practical strategies to help patients navigate cost and access challenges at the start of the year.

The neurologist at the University of Oklahoma Medical Center highlighted early diagnosis, prevention of secondary injury, and multimodal monitoring as key to improving patient outcomes in TBI. [WATCH TIME: 5 minutes]

At AAN 2026, an associate professor of neurology at University of Washington discussed how delays in antiamyloid treatment initiation for early Alzheimer disease may be driven by real-world factors. [WATCH TIME: 5 minutes]

A medical student at at Santa Casa de São Paulo School of Medical Sciences discussed the findings from a systematic review suggest potential biomarker-level benefits of estradiol-based hormone therapy in Alzheimer disease, but cautions that heterogeneous data limit firm conclusions. [WATCH TIME: 3 minutes]

Coordinated Duchenne care transitions align cardiology, pulmonary and neuromuscular handoffs, protecting families from risky gaps after 18.

Clinicians tailor Duchenne steroid therapy over time—balancing benefits, side effects, and family capacity for monitoring newer treatments like gene therapy and givinostat.

See how care coordinators sync cardiology, pulmonology and neuromuscular visits so Duchenne teens move to adult care without gaps.

Clinicians weigh vamorolone vs prednisone/deflazacort, tailoring growth and weight goals while managing tricky steroid switches and adrenal risks.

In the final episode, 'Multidisciplinary Approaches to Long-Term Narcolepsy Care,' the panelists explore the multidisciplinary challenges inherent in managing narcolepsy over the long term, opening with a candid discussion of how fragmented healthcare systems and limited communication infrastructure make true care coordination difficult. In practice, the burden of bridging different care teams often falls on the patient, with the expert panel encouraging patients to keep all providers informed of treatment changes to avoid conflicting approaches.

The associate professor of neurology at Mayo Clinic Rochester discussed why earlier detection of environmental risk in Parkinson disease remains difficult and how gene-environment research may help move the field forward. [WATCH TIME: 4 minutes]

Neurology News Network for the week ending April 18, 2026. [WATCH TIME: 5 minutes]

The senior global medical director at Sanofi discussed the ongoing burden of CIDP, highlighting diagnostic challenges, treatment gaps, and the need for improved biomarkers and emerging therapies. [WATCH TIME: 3 minutes]

This episode, titled 'Optimizing Narcolepsy Treatment Through Polypharmacy,' features panelists discussing the role of polypharmacy in narcolepsy treatment, challenging the notion that a single agent is sufficient for most patients. While research suggests roughly 60% of narcolepsy patients are on multiple medications, the expert panel notes that in their own clinical practices the rate is considerably higher, reflecting a more aggressive pursuit of optimal outcomes. The anticipated arrival of orexin receptor agonists is acknowledged as potentially transformative, though the expert panel stops short of assuming any single agent will address the full spectrum of narcolepsy symptoms.

Clinicians weigh vamorolone vs prednisone/deflazacort for young boys, balancing growth, weight, and adrenal safety during steroid transitions.

Duchenne care now reaches adulthood—discover when to plan transition, boost teen independence, and find adult clinics that support lifelong needs.