Latest Conference Coverage


Stewart Factor, MD: Long-Term Data on Apomorphine Sublingual Film in Parkinson

Stewart Factor, MD: Long-Term Data on Apomorphine Sublingual Film in Parkinson

September 17th 2020

The director of the Movement Disorders Program and Vance Lanier Chair of Neurology at Emory University School of Medicine gave his perspective on the interim findings of a long-term safety study of apomorphine sublingual film.


Addressing Loneliness and Social Isolation in Patients With Parkinson Disease

Addressing Loneliness and Social Isolation in Patients With Parkinson Disease

September 17th 2020

The director of the VA Southwest Parkinson’s Disease Research, Education, and Clinical Centers offered background the inspiration for the study and why loneliness should be addressed in these patients.


Asaff Harel, MD: Risk Factors for Severe COVID-19 Infection in Multiple Sclerosis

Asaff Harel, MD: Risk Factors for Severe COVID-19 Infection in Multiple Sclerosis

September 17th 2020

The neurologist at Lenox Hill Hospital detailed the findings of his observational study that looked at patterns of COVID-19 infections in patients with multiple sclerosis.


Satralizumab Reduces Risk of Relapse, Including in Treatment-Naïve NMOSD

Satralizumab Reduces Risk of Relapse, Including in Treatment-Naïve NMOSD

September 17th 2020

Two posters presented at MS 2020 confirm satralizumab’s ability to reduce protocol-defined relapse including in patients with treatment-naïve NMOSD.


Joaquim Ferreira, MD, PhD: Opicapone’s Use in Levodopa-Treated Patients With Parkinson Disease

Joaquim Ferreira, MD, PhD: Opicapone’s Use in Levodopa-Treated Patients With Parkinson Disease

September 16th 2020

The head of the Laboratory of Clinical Pharmacology and Therapeutics at the University of Lisbon gave his perspective on the importance of the study population of this analysis.


Apomorphine Sublingual Film Shows Long-Term Efficacy in OFF Episode Treatment

Apomorphine Sublingual Film Shows Long-Term Efficacy in OFF Episode Treatment

September 16th 2020

The recently approved apomorphine sublingual film (Kynmobi; Sunovion) maintained efficacy over the long-term, with at least 74% of patients experiencing full ON within 30 minutes post-dose at each time point.


THN102 Is Safe, Improves Excessive Daytime Sleepiness in Parkinson Disease

THN102 Is Safe, Improves Excessive Daytime Sleepiness in Parkinson Disease

September 16th 2020

The investigational drug consistently increased the proportion of patients no longer suffering from daytime sleepiness during treatment.


Jakob Dupont, MD: Phase 1 Data on Cell Therapy for Progressive MS

Jakob Dupont, MD: Phase 1 Data on Cell Therapy for Progressive MS

September 16th 2020

The executive vice president and head of global research and development at Atara Biotherapeutics spoke to the findings of a phase 1 study of the cell therapy ATA188.


Amantadine Shows Treatment Durability for Reducing OFF Time in Parkinson Disease

Amantadine Shows Treatment Durability for Reducing OFF Time in Parkinson Disease

September 15th 2020

The percentage of patients reporting no OFF time and no impact of OFF on daily function more than doubled by the first on-treatment visit in this open-label trial.


Indu Subramanian, MD: The Effect of Loneliness on Parkinson Disease Severity

Indu Subramanian, MD: The Effect of Loneliness on Parkinson Disease Severity

September 15th 2020

The director of the VA Southwest Parkinson’s Disease Research, Education and Clinical Centers discussed how loneliness can impact Parkinson disease severity and how holistic approaches to care may help.


Tau Levels May Predict Early Disability, Worse Prognosis in MS

Tau Levels May Predict Early Disability, Worse Prognosis in MS

September 15th 2020

Data show that higher CSF tau levels at diagnosis correlated with worse disability independent of age, though no such associations were identified with amyloid-beta.


Levodopa-Carbidopa Intestinal Gel Superior to Immediate Release Capsules for ON Time Without Dyskinesia

Levodopa-Carbidopa Intestinal Gel Superior to Immediate Release Capsules for ON Time Without Dyskinesia

September 15th 2020

Benefits of levodopa-carbidopa intestinal gel lasted throughout the day and showed greater benefits of continuous dopaminergic stimulation in disease control than immediate release oral capsules.


Opicapone Improves ON, OFF Time in Levodopa-Treated Patients With Parkinson Disease

Opicapone Improves ON, OFF Time in Levodopa-Treated Patients With Parkinson Disease

September 14th 2020

The COMT inhibitor, which was approved in April 2020, may be a worthwhile option as a first-line adjunctive treatment for those with Parkinson disease with motor fluctuations.


Levodopa-Carbidopa Intestinal Gel Effective for Dyskinesia in Advanced Parkinson Disease

Levodopa-Carbidopa Intestinal Gel Effective for Dyskinesia in Advanced Parkinson Disease

September 14th 2020

Improvement in dyskinesia occurred after 2 weeks of treatment with levodopa-carbidopa intestinal gel and was sustained throughout the study.


COVID-19 Has Negative Impact on Parkinson Disease Symptom Management

COVID-19 Has Negative Impact on Parkinson Disease Symptom Management

September 13th 2020

Supporting patient activation of their knowledge, skill, and confidence in managing their health may empower patients in times of stress.


Parkinson Disease Gene Therapy VY-AADC01 Proves Safe With Signs of Efficacy

Parkinson Disease Gene Therapy VY-AADC01 Proves Safe With Signs of Efficacy

September 13th 2020

Three-year data from a phase 1 study of Voyager Therapeutics’ VY-AADC01 suggest it is safe and offers potential benefits for patients with Parkinson disease.


Bilateral Focused Ultrasound Thalamotomy Safe, Effective in Essential Tremor

Bilateral Focused Ultrasound Thalamotomy Safe, Effective in Essential Tremor

September 12th 2020

Scores reflective of tremor in each body part and task performance improved by 71% in patients from baseline before first thalamotomy to 6 months after second thalamotomy.


Cannabinoid May Improve Nonmotor Symptoms in Parkinson Disease

Cannabinoid May Improve Nonmotor Symptoms in Parkinson Disease

September 12th 2020

Results from a phase 2 pilot study of nabilone in Parkinson disease suggest that the synthetic cannabinoid might hold therapeutic potential for nonmotor symptoms.


Ofatumumab Highly Effective in Treatment-Naïve Relapsing-Remitting Multiple Sclerosis

Ofatumumab Highly Effective in Treatment-Naïve Relapsing-Remitting Multiple Sclerosis

September 11th 2020

Treatment-naïve patients showed consistent results with the overall study population that was observed in the ASCLEPIOS I and II trials.


Disability, Economic Burden Greater in MS Patients With High Levels of Fatigue

Disability, Economic Burden Greater in MS Patients With High Levels of Fatigue

September 11th 2020

Patients with relapsing multiple sclerosis and high levels of fatigue were less likely to be employed full-time than those with MS with low fatigue.


Pitolisant Shows No Cardiac Safety Signals in Narcolepsy

Pitolisant Shows No Cardiac Safety Signals in Narcolepsy

September 4th 2020

Despite previous literature documenting cardiovascular disease comorbidity in patients with narcolepsy, pitolisant treatment did not demonstrate any cardiac safety signals.


Solriamfetol Improves Excessive Daytime Sleepiness and Driving Performance Ability

Solriamfetol Improves Excessive Daytime Sleepiness and Driving Performance Ability

September 1st 2020

The FDA-approved agent showed significant impact in decreasing standard deviation of lateral position, a measure used to assess driving performance.


Pitolisant Improves Daytime Sleepiness and Cataplexy in Severely Burdened Patients

Pitolisant Improves Daytime Sleepiness and Cataplexy in Severely Burdened Patients

September 1st 2020

Pooled data from 2 clinical trials of the H3-receptor antagonist/inverse agonist show it improved cataplexy and excessive daytime sleepiness in patients with narcolepsy who were most hampered by symptoms.


Marwan Sabbagh, MD

Marwan Sabbagh, MD: Observations From AAIC 2020

September 1st 2020

The director of the Lou Ruvo Center for Brain Health and neurologist at Cleveland Clinic detailed the state of Alzheimer disease and what research particularly grabbed his attention at AAIC 2020.


Lemborexant Demonstrates Efficacy in Elders

Lemborexant Demonstrates Efficacy in Elders

September 1st 2020

Already FDA approved for the treatment of insomnia in adults, lemborexant’s ability to improve sleep outcomes in the elderly was highlighted in a study presented at SLEEP 2020.


Lemborexant Improves Sleep Outcomes Following Placebo Randomization Switch

Lemborexant Improves Sleep Outcomes Following Placebo Randomization Switch

August 27th 2020

Benefit from lemborexant was evident after 1 month of switching from placebo to the active treatment and was sustained through the entirety of the 12-month trial.


Cognitive Behavioral Therapy for Insomnia Shows Multiple Benefits for Women

Cognitive Behavioral Therapy for Insomnia Shows Multiple Benefits for Women

August 27th 2020

Multiple abstracts at SLEEP 2020 show CBT-I’s success in aiding women with insomnia, including those going through pregnancy, and those who are veterans both with and without PTSD.


Katrina Celis, MD: Genetics and Their Role in Alzheimer Research, Clinical Care

Katrina Celis, MD: Genetics and Their Role in Alzheimer Research, Clinical Care

August 12th 2020

The postdoctoral fellow at the University of Miami Miller School of Medicine detailed the role that increased APOE ε4 expression can have on future research and clinical care.

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